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Inhibition of Bone Calcification by Sulphonamides

Abstract

THE recent demonstration by Golding and Silver1 that certain sulphonamides act as inhibitors of phosphatase in vitro has led us to present a preliminary report of our investigations on the effect of sulphonamides on bone formation in vivo.

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References

  1. Golding and Silver, demonstration to the Physiological Society, November 25, 1944.

  2. Benesch, R., Mawson, C. A., and Barron, N. S., Nature, 153, 138 (1944).

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BENESCH, R., CHANCE, M. & GLYNN, L. Inhibition of Bone Calcification by Sulphonamides. Nature 155, 203–204 (1945). https://doi.org/10.1038/155203a0

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