Abstract
IN 1931 Hartridge and West1 noted a rigidity-removing (lissive) action of curare in experimental parathyroid tetany in dogs. The application of the drug to diseases involving muscular rigidity in man was undertaken by West in a wide series of cases2. As it was observed quite early in the investigations that the lissive action was apparently only present in certain samples of curare and might be due to some constituent other than the curarines to which the classical action of curare is due, a broad chemical survey of the much neglected field of the curares was undertaken by the writer in close co-operation on the pharmacological side with Dr. Ranyard West.
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References
Brain, 54, 312; 1931.
Proc. Roy. Soc. Med., 25, 39; 1932.Lancet, p. 88 ; 1895.
Kew Bulletin, 8, 390; 1933.
Abhandl. Kgl. sächs. Ges. Wissensch., 22, 201; 1895.
H. King, Ann. Rep. Chem. Soc., 30, 242; 1933.
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KING, H. Curare. Nature 135, 469–470 (1935). https://doi.org/10.1038/135469b0
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DOI: https://doi.org/10.1038/135469b0
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