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Hexuronic (Ascorbic) Acid as the Antiscorbutic Factor, and its Chemical Determination

Abstract

ALTHOUGH it is known that specimens of hexuronic acid (since renamed ascorbic acid) possess antiscorbutic properties, it has remained to show whether this activity was an inherent property of the pure substance itself or ascribable to some associated impurity. Experiments to test the point have been carried out in this laboratory, as a result of which a very extensive and constant correlation has been established between vitamin C activity and hexuronic acid. Little doubt can therefore remain as to the identity of the two substances.

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BIRCH, T., HARRIS, L. & RAY, S. Hexuronic (Ascorbic) Acid as the Antiscorbutic Factor, and its Chemical Determination. Nature 131, 273–274 (1933). https://doi.org/10.1038/131273b0

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  • DOI: https://doi.org/10.1038/131273b0

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