Enhancing the efficiency of solar-driven water splitting is challenging but highly interesting. Here the authors report a dual spin-controlled 2D/3D perovskite photoelectrode that achieves 12.55% efficiency by utilizing the chiral-induced spin selectivity phenomenon.

Palladium-based catalysts are highly effective for the complete oxidation of methane. Here, the authors employ operando transmission electron microscopy, near-ambient pressure X-ray photoelectron spectroscopy, and density functional theory calculations to investigate the active state and catalytic function of Pd nanoparticles in methane oxidation.

Room temperature phosphorescent polymers have potential in a range of applications, but achieving the desired properties can be challenging. Here, the authors report the development of such polymer materials by doping with polyaromatic hydrocarbons.

This work reports a single-atom Ni incorporated CeO₂ catalyst that boosts the efficiency of solar CO₂ reduction under concentrated light irradiation.

Tungsten trioxide (WO₃) is considered the most promising photocatalyst for the highly selective oxidation of methane to formaldehyde, though the origins of its catalytic activity and reaction mechanism are still debated. Here, the authors use WO₃ with {001} and {110} facets as model photocatalysts, demonstrating that the photocatalytic oxidation of methane to formaldehyde in WO₃ depends on the surface structure, leading to different formaldehyde selectivity.

This study maps global tree composition in forests and assesses the impacts of historical forest cover loss and climate change. The results highlight the need for preserving the remaining large forest biomes, while regenerating degraded forests in a way that provides resilience against climate change.

Estimating weather-induced shocks on food production requires reliable global weather datasets. Here, the authors compare global (GMFD and ERA5-Land) and regional (PRISM) datasets, showing that global datasets can uncover non-linear temperature relationships despite their lower predictive skill.

Zhang et al. propose the ecological status of the ocean by considering microbial diversity, structure, and biogeochemical potential. Ecological status of 32.44% surface ocean will change due to climate change in 2100, assuming no policy intervention.

Alternative stable states in forests have implications for the biosphere. Here, the authors combine forest biodiversity observations and simulations revealing that leaf types across temperate regions of the NH follow a bimodal distribution suggesting signatures of alternative forest states.

This study presents EMDiffuse, a software suite based on diffusion models which augments electron microscopy imaging. EMDiffuse enhances electron microscopy images and enables isotropic reconstruction of volume electron microscopy data, suitable for investigating biological nanostructures.

Hematopoietic stem cells are generated during development, though how and when they become dormant long term-HSCs remains unclear. Here they show that retinoic acid receptor levels are regulated by a IκBα-PRC2 axis in HSCs, and that IκBα KO mice have HSCs that are fewer in number, but functionally and molecularly more dormant.

The mechanical properties of spider silk are a consequence of the structural organisation of proteins known as spidroins. Here the authors investigate the structure of the fibers formed by a C-terminal domain of a major spidroin: the study elucidates the mechanisms by which spidroins are transformed from soluble form into a fiber.

There are limited therapeutics available for treatment of mpox. In this study, the authors identify two non-competing human neutralizing monoclonal antibodies with protective effects against orthopoxvirus infection in a mouse model and structurally resolve the targeted epitope within the MPXV B6 protein.

Selection drives divergence between species, contributing to speciation, while simultaneously favoring extensive diversity that is maintained across populations within a species. This study demonstrates how the selection landscape is complex and multidimensional across three species of Phlox flowers.

Central memory CD8+ T cells (Tcm) are important for lasting anti-tumour immunity and their differentiation is determined by underpinning transcriptional and metabolic regulation. Authors here show that although microwave ablation (MWA) cancer therapy induces T cells to acquire some of the gene expression features of Tcms, but the full metabolic remodeling required for functionality is only achieved if glycolysis is inhibited simultaneously.

Robotic surgery has been demonstrated to improve short-term outcomes for patients with gastric cancer who received a gastrectomy, but the long-term effects are less clear. Here, the authors report the survival outcomes of their phase 2 randomized controlled trial comparing robotic to laparoscopic distal gastrectomy in patients with resectable gastric cancer.

The severity of SARS-CoV-2 infection varied over the course of the pandemic due to factors such as changes in variant characteristics and population immunity from previous infection or vaccination. Here, the authors estimate infection hospitalisation and infection fatality rates in England over time from the start of the pandemic until March 2023.

The clinical application of inhibitors targeting checkpoint kinase 1 (CHK1) is challenged by limited efficacy. Here, the authors identify that thioredoxin (Trx) system inhibition mediates sensitivity to CHK1 inhibitor via regulating the activity of ribonucleotide reductase, demonstrating the synergistic effect of CHK1 inhibitor and inhibitors targeting Trx system in lung cancer models.

The epigenetic changes underlying the heterogeneity of RA disease presentation have been the subject of intense scrutiny. In this study, the authors use multiple single-cell sequencing datasets to define ‘chromatin superstates’ in patients with RA, which associate with distinct transcription factors and disease phenotypes.

Modeled results show that rooftop solar reduced energy burden for most adopters in 2021 from a median of 3.3% to 2.6% with the average adopter seeing a 0.6 point ($691 annual) reduction in burden, accounting for costs, incentives, and savings.

Harnessing the potential of considerable food security efforts requires the ability to translate them into commercial applications. In this Perspective, the author explores the alternative protein source start-up landscape.

Decentralized management of distributed energy sources for lower energy costs is of high interest. Here, authors show how privacy and security concerns are addressed under a decentralization framework through blockchain and parallelizable algorithms.

Zhao P.J. and his colleagues uncover spatial directionality of urban mobility by using new metrics of anisotropy and centripetality. They find monocentric cities have longer commutes with city expansion, while polycentric cities maintain consistent commuting patterns.

People learn by observing others and from personal experience, but which strategy they favor varies. Here, the authors show that while some people dynamically arbitrate and switch to the strategy that is most reliable, others preferentially use one or a fixed mixture of strategies.