Materials-based control of stem cell fate is beginning to be rigorously combined with traditional soluble-factor approaches to better understand the cells' behaviour and maximize their potential for therapy.
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Dingal, P., Discher, D. Combining insoluble and soluble factors to steer stem cell fate. Nature Mater 13, 532–537 (2014). https://doi.org/10.1038/nmat3997
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DOI: https://doi.org/10.1038/nmat3997
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