Thrombotic microangiopathies articles from across Nature Portfolio

Thrombotic microangiopathies are a group of diseases caused by thrombosis in the microvasculature, they most frequently affect the brain and kidneys. Two prominent causes are thrombotic thrombocytopenic purpura and haemolytic uremic syndrome.

Latest Research and Reviews

Reviews | 05 May 2021

Thrombotic microangiopathy in aHUS and beyond: clinical clues from complement genetics

Knowledge of complement genetics has improved understanding of the pathogenesis of primary atypical haemolytic uraemic syndrome (aHUS). This Review summarizes current knowledge of complement genetics in aHUS and discusses how complement studies affect the management of patients with other thrombotic microangiopathies.
- Fadi Fakhouri
- & Véronique Frémeaux-Bacchi
Nature Reviews Nephrology 17, 543-553
Research
07 October 2019 | Open Access

Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism
- Karl E. Johansson
- , Anne-Lie Ståhl
- & Diana Karpman
Scientific Reports 9, 14362
Research | 01 April 2019

Complement-mediated microangiopathy in IgA nephropathy and IgA vasculitis with nephritis
- Jamie S. Chua
- , Malu Zandbergen
- & Ingeborg M. Bajema
Modern Pathology 32, 1147-1157
Research | 14 December 2018

Bevacizumab-associated glomerular microangiopathy
- Fermin Person
- , Markus M. Rinschen
- & Thorsten Wiech
Modern Pathology 32, 684-700
Research
14 November 2018 | Open Access

Radiation-induced premature cellular senescence involved in glomerular diseases in rats
- Sae Aratani
- , Masako Tagawa
- & Shuichi Tsuruoka
Scientific Reports 8, 16812
Reviews | 13 October 2017

Transplant glomerulopathy
- Edward J Filippone
- , Peter A McCue
- & John L Farber
Modern Pathology 31, 235-252