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| Open AccessLigand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms
- Spencer O. Moen
- , Thomas E. Edwards
- & Donald D. Lorimer
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| Open AccessInhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel
- Guglielmo Verona
- , P. Patrizia Mangione
- & Vittorio Bellotti
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| Open AccessRational Design of Protein C Activators
- Sergio Barranco-Medina
- , Mary Murphy
- & Nicola Pozzi
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| Open AccessStructural insights into the γ-lactamase activity and substrate enantioselectivity of an isochorismatase-like hydrolase from Microbacterium hydrocarbonoxydans
- Shuaihua Gao
- , Yu Zhou
- & Yue Feng
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| Open AccessFirst record of gregarines (Apicomplexa) in seminal vesicle of insect
- Glenda Dias
- , Romano Dallai
- & José Lino-Neto
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| Open AccessStructural Basis of Eco1-Mediated Cohesin Acetylation
- William C. H. Chao
- , Benjamin O. Wade
- & Martin R. Singleton
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| Open AccessCrystal structures reveal N-terminal Domain of Arabidopsis thaliana ClpD to be highly divergent from that of ClpC1
- Chinmayee Mohapatra
- , Manas Kumar Jagdev
- & Dileep Vasudevan
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| Open AccessCharacterization of long and stable de novo single alpha-helix domains provides novel insight into their stability
- Marcin Wolny
- , Matthew Batchelor
- & Michelle Peckham
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| Open AccessThe redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes
- Diana C. Rodriguez Camargo
- , Konstantinos Tripsianes
- & Bernd Reif
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| Open AccessThe Adhesion of Lactobacillus salivarius REN to a Human Intestinal Epithelial Cell Line Requires S-layer Proteins
- Ran Wang
- , Lun Jiang
- & Fazheng Ren
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| Open AccessExploring RNA conformational space under sparse distance restraints
- William R. Taylor
- & Russell S. Hamilton
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| Open AccessMechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι
- Rinku Jain
- , Jayati Roy Choudhury
- & Aneel K. Aggarwal
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Article
| Open AccessACCORD: an assessment tool to determine the orientation of homodimeric coiled-coils
- Byeong-Won Kim
- , Yang Ouk Jung
- & Hyun Kyu Song
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| Open AccessCrystal structures of highly simplified BPTIs provide insights into hydration-driven increase of unfolding enthalpy
- Mohammad Monirul Islam
- , Masafumi Yohda
- & Yutaka Kuroda
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Article
| Open AccessBiophysical studies suggest a new structural arrangement of crotoxin and provide insights into its toxic mechanism
- Carlos A. H. Fernandes
- , Wallance M. Pazin
- & Marcos R. M. Fontes
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| Open AccessMolecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation
- Yinglu Zhang
- , Chun-Min Shan
- & Songtao Jia
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| Open AccessChemosensory adaptations of the mountain fly Drosophila nigrosparsa (Insecta: Diptera) through genomics’ and structural biology’s lenses
- Francesco Cicconardi
- , Daniele Di Marino
- & Florian M. Steiner
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| Open AccessPRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3
- Huizhi Zhang
- , Guennadi Kozlov
- & Kalle Gehring
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| Open AccessCrystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C
- Roger M. Benoit
- , Martin A. Schärer
- & Richard A. Kammerer
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Article
| Open AccessDetermination of the pKa of the N-terminal amino group of ubiquitin by NMR
- Alain Oregioni
- , Benjamin Stieglitz
- & Tom Frenkiel
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| Open AccessTubZ filament assembly dynamics requires the flexible C-terminal tail
- Maria E. Fuentes-Pérez
- , Rafael Núñez-Ramírez
- & Maria A. Oliva
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| Open AccessHigh-resolution imaging of living mammalian cells bound by nanobeads-connected antibodies in a medium using scanning electron-assisted dielectric microscopy
- Tomoko Okada
- & Toshihiko Ogura
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| Open AccessA hydrophobic patch surrounding Trp154 in human neuroserpin controls the helix F dynamics with implications in inhibition and aggregation
- Mohammad Farhan Ali
- , Abhinav Kaushik
- & Mohamad Aman Jairajpuri
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Article
| Open AccessDistribution of valence electrons of the flavin cofactor in NADH-cytochrome b5 reductase
- Kiyofumi Takaba
- , Kazuki Takeda
- & Kunio Miki
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| Open AccessMembrane targeting of TIRAP is negatively regulated by phosphorylation in its phosphoinositide-binding motif
- Xiaolin Zhao
- , Wen Xiong
- & Daniel G. S. Capelluto
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| Open AccessStructure and dynamics of Type III periplasmic proteins VcFhuD and VcHutB reveal molecular basis of their distinctive ligand binding properties
- Shubhangi Agarwal
- , Sanjay Dey
- & Jhimli Dasgupta
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| Open AccessMolecular Basis of ABHD5 Lipolysis Activation
- Matthew A. Sanders
- , Huamei Zhang
- & James G. Granneman
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| Open AccessIn Vitro Characterization and Concerted Function of Three Core Enzymes of a Glycyl Radical Enzyme - Associated Bacterial Microcompartment
- Jan Zarzycki
- , Markus Sutter
- & Cheryl A. Kerfeld
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| Open AccessMechanistic insight into the substrate specificity of 1,2-β-oligoglucan phosphorylase from Lachnoclostridium phytofermentans
- Masahiro Nakajima
- , Nobukiyo Tanaka
- & Hiroyuki Nakai
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| Open AccessNMR metabolic fingerprints of murine melanocyte and melanoma cell lines: application to biomarker discovery
- Arquimedes Paixão de Santana-Filho
- , Thiago Jacomasso
- & Guilherme Lanzi Sassaki
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| Open AccessA Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro
- Deping Wang
- , Cheng Chen
- & Haitao Yang
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| Open AccessThe structural switch of nucleotide-free kinesin
- Luyan Cao
- , Soraya Cantos-Fernandes
- & Benoît Gigant
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| Open AccessArabidopsis thaliana dehydroascorbate reductase 2: Conformational flexibility during catalysis
- Nandita Bodra
- , David Young
- & Joris Messens
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| Open AccessConcentration-dependent oligomerization of an alpha-helical antifreeze polypeptide makes it hyperactive
- Sheikh Mahatabuddin
- , Yuichi Hanada
- & Sakae Tsuda
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| Open AccessStructural and functional characterization of deep-sea thermophilic bacteriophage GVE2 HNH endonuclease
- Likui Zhang
- , Dandan Xu
- & Yong Gong
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| Open AccessHeteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms
- Zheng Zhou
- , Taishan Hu
- & Ning Qin
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| Open AccessDimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases
- Dom Bellini
- , Sam Horrell
- & Martin A. Walsh
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| Open AccessStability, structural and functional properties of a monomeric, calcium–loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis
- Sara E. Cannella
- , Véronique Yvette Ntsogo Enguéné
- & Alexandre Chenal
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| Open AccessStructural variability of E. coli thioredoxin captured in the crystal structures of single-point mutants
- Martín E. Noguera
- , Diego S. Vazquez
- & Javier Santos
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| Open AccessLumican Peptides: Rational Design Targeting ALK5/TGFBRI
- Tarsis Ferreira Gesteira
- , Vivien J. Coulson-Thomas
- & Winston W.-Y. Kao
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| Open AccessStructure of an octameric form of the minichromosome maintenance protein from the archaeon Pyrococcus abyssi
- Giuseppe Cannone
- , Silvia Visentin
- & Laura Spagnolo
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| Open AccessThe earliest molecular response to stretch of insect flight muscle as revealed by fast X-ray diffraction recording
- Hiroyuki Iwamoto
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| Open AccessTargeting the molecular chaperone SlyD to inhibit bacterial growth with a small molecule
- Amit Kumar
- & Jochen Balbach
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| Open AccessStructural basis for redox sensitivity in Corynebacterium glutamicum diaminopimelate epimerase: an enzyme involved in l-lysine biosynthesis
- Hye-Young Sagong
- & Kyung-Jin Kim
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| Open AccessStructural insights into human angiogenin variants implicated in Parkinson’s disease and Amyotrophic Lateral Sclerosis
- William J. Bradshaw
- , Saima Rehman
- & K. Ravi Acharya
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| Open AccessStructural basis of the interaction between Topoisomerase IIIβ and the TDRD3 auxiliary factor
- Sakurako Goto-Ito
- , Atsushi Yamagata
- & Shuya Fukai
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| Open AccessQuality Evaluation Focusing on Tissue Fractal Dimension and Chemical Changes for Frozen Tilapia with Treatment by Tangerine Peel Extract
- Qi He
- , Zhao Yang
- & Shang-Tian Yang
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| Open AccessStoichiometry and structure of a lantibiotic maturation complex
- Jens Reiners
- , André Abts
- & Lutz Schmitt
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| Open AccessHigh affinity anchoring of the decoration protein pb10 onto the bacteriophage T5 capsid
- Emeline Vernhes
- , Madalena Renouard
- & Pascale Boulanger