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| Open AccessDestabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin
- Shoeb Ahmad
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| Open AccessConformational stability of digestion-resistant peptides of peanut conglutins reveals the molecular basis of their allergenicity
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| Open AccessIdentification, Characterization and X-ray Crystallographic Analysis of a Novel Type of Mannose-Specific Lectin CGL1 from the Pacific Oyster Crassostrea gigas
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| Open AccessNMR Characterization of Information Flow and Allosteric Communities in the MAP Kinase p38γ
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| Open AccessNew insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit
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| Open AccessFunctional map of arrestin binding to phosphorylated opsin, with and without agonist
- Christian Peterhans
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| Open AccessComparative Structural and Computational Analysis Supports Eighteen Cellulose Synthases in the Plant Cellulose Synthesis Complex
- B. Tracy Nixon
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| Open AccessStructural and functional characterization of the CAP domain of pathogen-related yeast 1 (Pry1) protein
- Rabih Darwiche
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| Open AccessSTARD6 on steroids: solution structure, multiple timescale backbone dynamics and ligand binding mechanism
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| Open AccessAllosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2
- Matej Janeček
- , Maxim Rossmann
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| Open AccessEffects of the linker region on the structure and function of modular GH5 cellulases
- Diego M. Ruiz
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| Open AccessStructural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
- Sun-Yong Kim
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| Open AccessStructural insights of a hormone sensitive lipase homologue Est22
- Jing Huang
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| Open AccessA new autoinhibited kinase conformation reveals a salt-bridge switch in kinase activation
- Qiang Wei
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| Open AccessCrystal structure of MytiLec, a galactose-binding lectin from the mussel Mytilus galloprovincialis with cytotoxicity against certain cancer cell types
- Daiki Terada
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| Open AccessStructure of neprilysin in complex with the active metabolite of sacubitril
- Nikolaus Schiering
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- & Muneto Mogi
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| Open AccessA humanized anti-DLL4 antibody promotes dysfunctional angiogenesis and inhibits breast tumor growth
- Xuelian Jia
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| Open AccessConformational flexibility related to enzyme activity: evidence for a dynamic active-site gatekeeper function of Tyr215 in Aerococcus viridans lactate oxidase
- Thomas Stoisser
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| Open AccessAmicoumacin A induces cancer cell death by targeting the eukaryotic ribosome
- Irina V. Prokhorova
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- & Sergey E. Dmitriev
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| Open AccessCompressed Sensing Electron Tomography for Determining Biological Structure
- Matthew D. Guay
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| Open AccessCrystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding
- Haixia Zhu
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- & Ye Ni
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| Open AccessStructure of the host-recognition device of Staphylococcus aureus phage ϕ11
- Cengiz Koç
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- & Thilo Stehle
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| Open AccessScreening of saponins and sapogenins from Medicago species as potential PPARγ agonists and X-ray structure of the complex PPARγ/caulophyllogenin
- Roberta Montanari
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| Open Access1H-detected solid-state NMR of proteins entrapped in bioinspired silica: a new tool for biomaterials characterization
- Enrico Ravera
- , Linda Cerofolini
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| Open AccessStructure and function of chicken interleukin-1 beta mutants: uncoupling of receptor binding and in vivo biological activity
- Wen-Ting Chen
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| Open AccessStructural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity
- Giuliana Fusco
- , Alfonso De Simone
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| Open AccessPeptide aromatic interactions modulated by fluorinated residues: Synthesis, structure and biological activity of Somatostatin analogs containing 3-(3′,5′difluorophenyl)-alanine
- Pablo Martín-Gago
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- & Antoni Riera
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| Open AccessStructural flexibility of the periplasmic protein, FlgA, regulates flagellar P-ring assembly in Salmonella enterica
- Hideyuki Matsunami
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| Open AccessStructure and calcium-binding studies of calmodulin-like domain of human non-muscle α-actinin-1
- Sara Drmota Prebil
- , Urška Slapšak
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| Open AccessThe alterations in the extracellular matrix composition guide the repair of damaged liver tissue
- Mariliis Klaas
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| Open AccessUnexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7
- Menachem J. Gunzburg
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| Open AccessImmuno-targeting the multifunctional CD38 using nanobody
- Ting Li
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| Open AccessCharacterisation of assembly and ubiquitylation by the RBCC motif of Trim5α
- Jeremy R. Keown
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- & David C. Goldstone
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| Open AccessProtein rethreading: A novel approach to protein design
- Sayeh Agah
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| Open AccessStructural characterization of CYP144A1 – a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis
- Jude Chenge
- , Madeline E. Kavanagh
- & Andrew W. Munro
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| Open AccessSolution structure and binding specificity of the p63 DNA binding domain
- Andreas Enthart
- , Christian Klein
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| Open AccessNeuron-Like Networks Between Ribosomal Proteins Within the Ribosome
- Olivier Poirot
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| Open AccessMolecular Architecture of Yeast Chromatin Assembly Factor 1
- Daegeun Kim
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| Open AccessStructure-based site-directed photo-crosslinking analyses of multimeric cell-adhesive interactions of voltage-gated sodium channel β subunits
- Hideaki Shimizu
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| Open AccessStructure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) α-kinase domain apoenzyme reveals a novel autoinhibited conformation
- Qilu Ye
- , Yidai Yang
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| Open AccessGenetic manipulation of iron biomineralization enhances MR relaxivity in a ferritin-M6A chimeric complex
- Marina Radoul
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- & Raz Zarivach
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| Open AccessStructural and functional insights into the E3 ligase, RNF126
- Ewelina M. Krysztofinska
- , Santiago Martínez-Lumbreras
- & Rivka L. Isaacson
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| Open AccessA rationally engineered yeast pyruvyltransferase Pvg1p introduces sialylation-like properties in neo-human-type complex oligosaccharide
- Yujiro Higuchi
- , Sho Yoshinaga
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| Open AccessStructural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor
- Stephanie Hennen
- , János T. Kodra
- & Steffen Reedtz-Runge
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| Open AccessTriazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase
- Alia A. Sagatova
- , Mikhail V. Keniya
- & Brian C. Monk
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| Open AccessMolecular Mechanism for Conformational Dynamics of Ras·GTP Elucidated from In-Situ Structural Transition in Crystal
- Shigeyuki Matsumoto
- , Nao Miyano
- & Fumi Shima
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| Open AccessImaging of bacterial multicellular behaviour in biofilms in liquid by atmospheric scanning electron microscopy
- Shinya Sugimoto
- , Ken-ichi Okuda
- & Chikara Sato
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| Open AccessTwo common structural motifs for TCR recognition by staphylococcal enterotoxins
- Karin E. J. Rödström
- , Paulina Regenthal
- & Karin Lindkvist-Petersson
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| Open AccessSolution structure of the isolated histone H2A-H2B heterodimer
- Yoshihito Moriwaki
- , Tsutomu Yamane
- & Yoshifumi Nishimura