Schizosaccharomyces pombe articles from across Nature Portfolio

Schizosaccharomyces pombe, or fission yeast, is a unicellular fungus and a model organism used to study subjects including cell cycle control, DNA replication and genome integrity.

Latest Research and Reviews

Research
01 March 2019 | Open Access

Systematic analysis reveals the prevalence and principles of bypassable gene essentiality

An essential gene may become non-essential when another gene is mutated. Here, the authors investigate this type of digenic interaction, termed ‘bypass of essentiality’, in the fission yeast Schizosaccharomyces pombe, and show that bypassable essential genes are common and share certain features.
- Jun Li
- , Hai-Tao Wang
- & Li-Lin Du
Nature Communications 10, 1002
Research
12 October 2015 | Open Access

Wall mechanics and exocytosis define the shape of growth domains in fission yeast

Cell shape is determined by a combination of biochemical regulation and mechanical forces. By imaging the dynamic behaviour of growth regulatory proteins in fission yeast and integrating these data within a mechanical model, Abenza et al. find that exocytosis plays a dominant role in shaping growth domains.
- Juan F. Abenza
- , Etienne Couturier
- & Rafael E. Carazo Salas
Nature Communications 6, 8400
Research
20 May 2015 | Open Access

The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome

The evolutionarily conserved MTREC complex promotes degradation of meiotic mRNAs and regulatory ncRNAs. Here the authors show that MTREC also targets cryptic unstable transcripts and unspliced pre-mRNAs for degradation by the nuclear exosome, while the TRAMP complex has only a minor role in this process.
- Yang Zhou
- , Jianguo Zhu
- & Tamás Fischer
Nature Communications 6, 7050
Research
13 March 2015 | Open Access

Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition
- Xin Gong
- , Jingxian Li
- & Nieng Yan
Cell Research 25, 401-411
Protocols | 02 January 2014

Synchronized fission yeast meiosis using an ATP analog–sensitive Pat1 protein kinase
- Lubos Cipak
- , Silvia Polakova
- & Juraj Gregan
Nature Protocols 9, 223-231
Research | 16 May 2010

Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe

Genome-wide single-gene deletion libraries can be important tools for understanding the molecular workings of an organism, but have only been created for a single eukaryotic species, Saccharomyces cerevisiae. Now, Kim et al. present a second collection of deletion mutants that covers 98.4% of the genes of Schizosaccharomyces pombe, allowing a systematic comparison of gene essentiality and knockout phenotypes between two eukaryotic species.
- Dong-Uk Kim
- , Jacqueline Hayles
- & Kwang-Lae Hoe
Nature Biotechnology 28, 617-623

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News and Comment

Research Highlights | 15 November 2016

Breaking down the NSA1
- Grant Miura
Nature Chemical Biology 12, 989
Correspondence | 19 June 2015

Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2
- Wei Deng
- , Jian Wu
- & Ming Lei
Cell Research 25, 881-884
Research Highlights | 29 October 2014

3D genome architecture — of loops and globules
- Linda Koch
Nature Reviews Genetics 15, 780
Research Highlights | 11 September 2013

Rearrangements for fitness
- Hannah Stower
Nature Reviews Genetics 14, 677
Research Highlights | 27 October 2010

Cell biology: Spindle-free division in yeast

Nature 467, 1009
Correspondence | 13 July 2010

A genome-wide screen for Schizosaccharomyces pombe deletion mutants that affect telomere length
- Ning-Ning Liu
- , Tian Xu Han
- & Jin-Qiu Zhou
Cell Research 20, 963-965

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Schizosaccharomyces pombe articles from across Nature Portfolio

Latest Research and Reviews

Systematic analysis reveals the prevalence and principles of bypassable gene essentiality

Wall mechanics and exocytosis define the shape of growth domains in fission yeast

The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome

Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition

Synchronized fission yeast meiosis using an ATP analog–sensitive Pat1 protein kinase

Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe

News and Comment

Breaking down the NSA1

Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2

3D genome architecture — of loops and globules

Rearrangements for fitness

Cell biology: Spindle-free division in yeast

A genome-wide screen for Schizosaccharomyces pombe deletion mutants that affect telomere length

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