SARS-CoV-2

SARS-CoV-2 is a positive-sense single-stranded RNA virus. It is contagious in humans and is the cause of the coronavirus disease 2019 (COVID-19).

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News & Views | 19 April 2021

Immunity after SARS-CoV-2 infections
- Prasanna Jagannathan
- & Taia T. Wang
Nature Immunology, 1-2

Latest Research and Reviews

Research | 22 April 2021

High-dimensional characterization of post-acute sequalae of COVID-19
- Ziyad Al-Aly
- , Yan Xie
- & Benjamin Bowe
Nature, 1-8
Research
22 April 2021 | Open Access

Leveraging community mortality indicators to infer COVID-19 mortality and transmission dynamics in Damascus, Syria

Reported COVID-19 mortality rates have been relatively low in Syria, but there has been concern about overwhelmed health systems. Here, the authors use community mortality indicators and estimate that <3% of COVID-19 deaths in Damascus were reported as of 2 September 2020.
- Oliver J. Watson
- , Mervat Alhaffar
- & Patrick Walker
Nature Communications 12, 2394
Research
21 April 2021 | Open Access

SARS-CoV-2 shifting transmission dynamics and hidden reservoirs potentially limit efficacy of public health interventions in Italy

Giovanetti et al. examine SARS-CoV-2 transmission dynamics in Italy using phylodynamic analysis of viral genetic and epidemiological data. They present evidence to suggest that the efficacy of public health interventions is limited by the size and structure of epidemic reservoirs, which may influence vaccination programmes.
- Marta Giovanetti
- , Eleonora Cella
- & Massimo Ciccozzi
Communications Biology 4, 489
Research
20 April 2021 | Open Access

Optimal, near-optimal, and robust epidemic control

The COVID-19 pandemic has demonstrated the need for non-pharmaceutical epidemic mitigation strategies that can be effective even if they are limited in duration. Here, the authors derive analytically optimal and near-optimal time-limited strategies for limiting the epidemic peak in the Susceptible-Infectious-Recovered model and show that, due to the sensitivity of such strategies to implementation errors, timely action is fundamental to non-pharmaceutical disease control.
- Dylan H. Morris
- , Fernando W. Rossine
- & Simon A. Levin
Communications Physics 4, 78
Research
20 April 2021 | Open Access

Single-cell multi-omics analysis of the immune response in COVID-19

Transcriptomic and proteomic profiling of blood samples from individuals with COVID-19 reveals immune cell and hematopoietic progenitor cell alterations that are differentially associated with disease severity.
- Emily Stephenson
- , Gary Reynolds
- & Muzlifah Haniffa
Nature Medicine, 1-13
Research | 19 April 2021

Adjuvanting a subunit COVID-19 vaccine to induce protective immunity
- Prabhu S. Arunachalam
- , Alexandra C. Walls
- & Bali Pulendran
Nature, 1-10

All Research & Reviews

News and Comment

Editorial | 21 April 2021

Three million COVID deaths is a grim milestone

The COVID-19 pandemic has taken too many lives, and has set back efforts to tackle other infectious diseases.

Nature 592, 488
Editorial | 21 April 2021

Africa’s vaccines revolution must have research at its core

It’s an injustice that Africa has to import 99% of its vaccines. COVID has sparked a push for change — and researchers have a crucial role.

Nature 592, 487-488
News | 21 April 2021

India’s massive COVID surge puzzles scientists

The virus is spreading faster than ever before in India despite previous high infection rates in megacities, which should have conferred some protection.
- Smriti Mallapaty
Nature
News | 21 April 2021

Every T. rex, COVID asthma drug and variant control

The latest science news, in brief.

Nature 592, 493
News | 21 April 2021

How COVID spurred Africa to plot a vaccines revolution

For decades, Africa has imported 99% of its vaccines. Now the continent’s leaders want to bring manufacturing home.
- Aisling Irwin
Nature
News | 21 April 2021

How COVID hurt the fight against other dangerous diseases

Campaigns to battle tuberculosis, measles and polio have all been set back.
- Leslie Roberts
Nature 592, 502-504

All News & Comment

SARS-CoV-2

Featured

Immunity after SARS-CoV-2 infections

Latest Research and Reviews

High-dimensional characterization of post-acute sequalae of COVID-19

Leveraging community mortality indicators to infer COVID-19 mortality and transmission dynamics in Damascus, Syria

SARS-CoV-2 shifting transmission dynamics and hidden reservoirs potentially limit efficacy of public health interventions in Italy

Optimal, near-optimal, and robust epidemic control

Single-cell multi-omics analysis of the immune response in COVID-19

Adjuvanting a subunit COVID-19 vaccine to induce protective immunity

News and Comment

Three million COVID deaths is a grim milestone

Africa’s vaccines revolution must have research at its core

India’s massive COVID surge puzzles scientists

Every T. rex, COVID asthma drug and variant control

How COVID spurred Africa to plot a vaccines revolution

How COVID hurt the fight against other dangerous diseases

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