RNA vaccines articles within Nature Reviews Clinical Oncology

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• Review Article | 17 May 2024

  Cancer mRNA vaccines: clinical advances and future opportunities

  Following their successful implementation in the COVID-19 pandemic, the technology behind mRNA vaccines is now being applied to cancer. In this Review, the authors described the several decades of development of mRNA vaccines for patients with cancer, including initial developments in this area involving cell-based vaccines as well as more recent developments with nanoparticle-encapsulated vaccines, which are beginning to show promising clinical activity.

  • Elias J. Sayour
  • , David Boczkowski
  •  & Smita K. Nair

• Review Article | 11 March 2022

  COVID-19 vaccines in patients with cancer: immunogenicity, efficacy and safety

  Vaccination against COVID-19 confers robust protection from severe disease. However, the extent to which this applies to patients with cancer remains uncertain given that these patients were excluded from most of the pivotal studies. In this Review, the authors provide an overview of the efficacy and immunogenicity of COVID-19 vaccines in patients with cancer, and discuss alternatives to vaccination for those who might be unable to develop a proficient immune response following vaccination.

  • Annika Fendler
  • , Elisabeth G. E. de Vries
  •  & Marie von Lilienfeld-Toal