The prostate is a secretory gland situated in the pelvis of males; it sits underneath the bladder and surrounds the urethra. Fluid produced by the prostate is the main component of semen.

Latest Research and Reviews

News and Comment

  • Comments & Opinion |

    Prostate cancer disproportionately affects Black men; the reason for this phenomenon is unclear. The role of the health-care provider is important in screening for prostate cancer, advising on treatment and ensuring completeness of therapy. Cultural competency is necessary in health-care providers as, for most men in Europe, Australasia and the USA, the ethnicity and/or race of the urologist will be discordant with that of the patient.

    • Francis I. Chinegwundoh
  • Comments & Opinion |

    Focus on quality of life after prostate cancer is vital to improve patient care. Improved assessment and proactive management of post-treatment functional outcomes is essential. Many aspects of the patients’ aftercare need to be improved in order to set up a clear path following prostatectomy. These improvements will enable a timely and efficient escalation of treatment and ameliorate patients’ survivorship experience.

    • Findlay MacAskill
    • , Arun Sahai
    •  & Sachin Malde
  • News & Views |

    Serum PSA testing can identify men with clinically significant prostate cancer but exposes many more men to the diagnosis of indolent tumours. Benafif and colleagues have published the results of the BARCODE1 pilot study, in which they propose using germline single-nucleotide polymorphisms to identify men with a genetic risk of developing prostate cancer. Based on their preliminary findings, changing the current prostate cancer screening paradigm will be a challenge.

    • Peter C. Albertsen
  • News & Views |

    More than 50 clinical trials are currently exploring the combination of immunotherapy and other approved treatments for advanced prostate cancer. The results from a phase II trial of sipuleucel-T with or without radium-223 in patients with metastatic castration-resistant prostate cancer were recently published with intriguing findings.

    • Abhishek Srivastava
    •  & Neal D. Shore
  • Comments & Opinion |

    New technical modifications enable transperineal prostate biopsy to be performed in the ambulatory setting under local anaesthesia. Although a variety of techniques for administration of local anaesthetic during transperineal prostate biopsy have been described, no consensus exists regarding the most effective method to use. Thus, ample opportunity exists for procedural innovation and future study on this topic.

    • Spyridon P. Basourakos
    • , Mathew J. Allaway
    •  & Michael A. Gorin