Population genetics

Definition

Population genetics is the study of the genetic composition of populations, including distributions and changes in genotype and phenotype frequency in response to the processes of natural selection, genetic drift, mutation and gene flow.

Latest Research and Reviews

  • Research |

    Whole-genome sequencing data of 14,688 Icelanders, including 1,548 parent–offspring trios, show how the age and sex of parents affect the rate and spectrum of de novo mutations.

    • Hákon Jónsson
    • , Patrick Sulem
    • , Birte Kehr
    • , Snaedis Kristmundsdottir
    • , Florian Zink
    • , Eirikur Hjartarson
    • , Marteinn T. Hardarson
    • , Kristjan E. Hjorleifsson
    • , Hannes P. Eggertsson
    • , Sigurjon Axel Gudjonsson
    • , Lucas D. Ward
    • , Gudny A. Arnadottir
    • , Einar A. Helgason
    • , Hannes Helgason
    • , Arnaldur Gylfason
    • , Adalbjorg Jonasdottir
    • , Aslaug Jonasdottir
    • , Thorunn Rafnar
    • , Mike Frigge
    • , Simon N. Stacey
    • , Olafur Th. Magnusson
    • , Unnur Thorsteinsdottir
    • , Gisli Masson
    • , Augustine Kong
    • , Bjarni V. Halldorsson
    • , Agnar Helgason
    • , Daniel F. Gudbjartsson
    •  & Kari Stefansson
  • Research | | open

    The Singapore Genome Variation projects characterized the genetics of Singapore’s Chinese, Malay, and Indian populations. The Singapore Integrative Omics Study introduced here goes further in providing multi-omic measurements in individuals from these populations, including genetic, transcriptome, lipidome, and lifestyle data, and will facilitate the study of common diseases in Asian communities.

    • Woei-Yuh Saw
    • , Erwin Tantoso
    • , Husna Begum
    • , Lihan Zhou
    • , Ruiyang Zou
    • , Cheng He
    • , Sze Ling Chan
    • , Linda Wei-Lin Tan
    • , Lai-Ping Wong
    • , Wenting Xu
    • , Don Kyin Nwe Moong
    • , Yenly Lim
    • , Bowen Li
    • , Nisha Esakimuthu Pillai
    • , Trevor A. Peterson
    • , Tomasz Bielawny
    • , Peter J. Meikle
    • , Piyushkumar A. Mundra
    • , Wei-Yen Lim
    • , Ma Luo
    • , Kee-Seng Chia
    • , Rick Twee-Hee Ong
    • , Liam R. Brunham
    • , Chiea-Chuen Khor
    • , Heng Phon Too
    • , Richie Soong
    • , Markus R. Wenk
    • , Peter Little
    •  & Yik-Ying Teo
  • Research | | open

    • Hákon Jónsson
    • , Patrick Sulem
    • , Birte Kehr
    • , Snaedis Kristmundsdottir
    • , Florian Zink
    • , Eirikur Hjartarson
    • , Marteinn T. Hardarson
    • , Kristjan E. Hjorleifsson
    • , Hannes P. Eggertsson
    • , Sigurjon Axel Gudjonsson
    • , Lucas D. Ward
    • , Gudny A. Arnadottir
    • , Einar A. Helgason
    • , Hannes Helgason
    • , Arnaldur Gylfason
    • , Adalbjorg Jonasdottir
    • , Aslaug Jonasdottir
    • , Thorunn Rafnar
    • , Soren Besenbacher
    • , Michael L. Frigge
    • , Simon N. Stacey
    • , Olafur Th. Magnusson
    • , Unnur Thorsteinsdottir
    • , Gisli Masson
    • , Augustine Kong
    • , Bjarni V. Halldorsson
    • , Agnar Helgason
    • , Daniel F. Gudbjartsson
    •  & Kari Stefansson
    Scientific Data 4, 170115

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