Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Oscillators are physical systems whose evolution over time varies repeatedly around a central state of equilibrium. Oscillating cycles that are more or less periodic are found in all sectors of science, from quantum physics to cell biology, sociology or cosmology.
Many clock proteins contain intrinsically disordered regions, but how these regions mediate protein interactions is poorly understood. Here, the authors identify charge blocks within a disordered clock protein that regulate circadian timing.
The authors unveil a scaling relationship between DNA damage, p53-p21 signaling, and proliferation. The analysis reveals unexpected temporal shifts in p53 and p21 dynamics, encoding damage strength and driving proliferation changes.
Mutations of several genes cause variable phenotypes. Here, the authors show stochastic her1 and her7 gene expression, which is affected by environmental conditions, underlies variability of somite segmentation defects.
Large-scale multi-structure recordings in freely behaving rats reveal that 5-HT2AR and NMDAR psychedelics induce similar hyper-synchronous states in the cognitive-limbic cortex-basal ganglia system
