Organogenesis articles from across Nature Portfolio

Organogenesis is the process by which the internal organs and specific structures such as the limb are formed during development of an organism. Organogenesis involves the coordination of multiple developmental processes such as embryonic induction, pattern formation, morphogenesis, cell proliferation and differentiation.

Latest Research and Reviews

Research | 10 May 2023

A pan-grass transcriptome reveals patterns of cellular divergence in crops

Complementary single-cell and single-nucleus transcriptomic analyses of Zea mays, Sorghum bicolor and Setaria viridis root cells provide insights into the evolution of cell types and gene modules that control key traits in these important crop species.
- Bruno Guillotin
- , Ramin Rahni
- & Kenneth D. Birnbaum
Nature 617, 785-791
Research | 09 May 2023

Association of antenatal corticosteroids with kidney function in adolescents born preterm with very low birth weight
- Whitney N. Floyd
- , Daniel P. Beavers
- & Andrew M. South
Journal of Perinatology, 1-7
Research
09 May 2023 | Open Access

Molecular mechanisms of tubulogenesis revealed in the sea star hydro-vascular organ

Understanding how cells organize into organs is a key effort in developmental biology. Here the authors introduce the sea star hydrovascular organ as a genetically tractable system to understand the contribution of cell migration and signaling pathways in tubulogenesis.
- Margherita Perillo
- , S. Zachary Swartz
- & Gary M. Wessel
Nature Communications 14, 2402
Research
08 May 2023 | Open Access

Multimodal spatiotemporal phenotyping of human retinal organoid development

A multimodal atlas of retinal organoid development shows spatial interactions over time.
- Philipp Wahle
- , Giovanna Brancati
- & J. Gray Camp
Nature Biotechnology, 1-11
Research
28 April 2023 | Open Access

USP7 controls NGN3 stability and pancreatic endocrine lineage development

Tightly controlled NGN3 expression is essential for endocrine cell generation in the developing pancreas, with dysregulation leading to hyperglycemia in mice. Here they identify USP7 as a key post-translational regulator of NGN3 stability and show that this axis is required for endocrine development and beta-cell differentiation.
- Teodora Manea
- , Jessica Kristine Nelson
- & Rocio Sancho
Nature Communications 14, 2457
Research
26 April 2023 | Open Access

A CRISPR/Cas9-generated mutation in the zebrafish orthologue of PPP2R3B causes idiopathic scoliosis
- Marian Seda
- , Berta Crespo
- & Dagan Jenkins
Scientific Reports 13, 6783

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News and Comment

News & Views | 22 March 2023

Single-cell and spatial transcriptomics during human organogenesis

The molecular and cellular events that occur during the onset of human organogenesis remain mysterious. We used single-cell and spatial transcriptomics to provide a global view of human embryonic cell-type specification, shedding light on developmental processes such as axial patterning, stage transition, and differences between human and mouse embryonic development.

Nature Cell Biology 25, 522-523
Research Highlights | 26 August 2022

YAP and TAZ regulate stromal cell development
- Monica Wang
Nature Reviews Nephrology 18, 605
Research Highlights | 25 August 2022

To fuse or to divide, that was the question

Elizabeth Chen looks back on the work by Beatrice Mintz and Wilber Baker (1967) that settled the debate on the origin of multinucleation in skeletal muscle cells.
- Elizabeth H. Chen
Nature Reviews Molecular Cell Biology 24, 5
Research Highlights | 19 May 2022

A panoramic view of mouse organogenesis

A recent study reports the development of Stereo-seq (spatial enhanced resolution omics-sequencing) and its application to generate a spatiotemporal transcriptomic atlas of mouse organogenesis.
- Linda Koch
Nature Reviews Genetics 23, 393
News & Views | 18 May 2022

A quantitative and temporal 3D atlas of embryonic mouse heart formation

Using a quantitative statistical approach, we created a 3D atlas of embryonic cardiac morphogenesis from a collection of mouse specimens. The atlas includes the average shape of tissue geometry over time and its range of variability, and it enabled us to identify the onset of cardiac left–right asymmetry.

Nature Cardiovascular Research 1, 550-551
Research Highlights | 08 April 2022

In vivo traction force microscopy

Embryogram allows stress measurements during migration of the lateral line primordium in zebrafish embryos.
- Nina Vogt
Nature Methods 19, 399

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Organogenesis articles from across Nature Portfolio

Latest Research and Reviews

A pan-grass transcriptome reveals patterns of cellular divergence in crops

Association of antenatal corticosteroids with kidney function in adolescents born preterm with very low birth weight

Molecular mechanisms of tubulogenesis revealed in the sea star hydro-vascular organ

Multimodal spatiotemporal phenotyping of human retinal organoid development

USP7 controls NGN3 stability and pancreatic endocrine lineage development

A CRISPR/Cas9-generated mutation in the zebrafish orthologue of PPP2R3B causes idiopathic scoliosis

News and Comment

Single-cell and spatial transcriptomics during human organogenesis

YAP and TAZ regulate stromal cell development

To fuse or to divide, that was the question

A panoramic view of mouse organogenesis

A quantitative and temporal 3D atlas of embryonic mouse heart formation

In vivo traction force microscopy

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Organogenesis articles from across Nature Portfolio

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