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| Open AccessSynergistic silencing of α-globin and induction of γ-globin by histone deacetylase inhibitor, vorinostat as a potential therapy for β-thalassaemia
- Sachith Mettananda
- , Nirmani Yasara
- & Doug Higgs
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| Open AccessTGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor
- Sabine Klein
- , Carola-Ellen Kleine
- & Jonel Trebicka
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| Open AccessFibrinogen binding is affected by amino acid substitutions in C-terminal repeat region of fibronectin binding protein A
- Nadia N. Casillas-Ituarte
- , Alex C. DiBartola
- & Batu K. Sharma-Kuinkel
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| Open AccessProtective effect of nobiletin on isolated human islets survival and function against hypoxia and oxidative stress-induced apoptosis
- Somayeh Keshtkar
- , Maryam Kaviani
- & Negar Azarpira
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| Open AccessNanoencapsulated betulinic acid analogue distinctively improves colorectal carcinoma in vitro and in vivo
- Debasmita Dutta
- , Brahamacharry Paul
- & Mita Chatterjee Debnath
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| Open AccessUp-regulation of heat shock protein 27 inhibits apoptosis in lumbosacral nerve root avulsion-induced neurons
- Zhi-bin Zhou
- , Gao-xiang Huang
- & Lei Zhu
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| Open AccessDetection and targeting insulin growth factor receptor type 2 (IGF2R) in osteosarcoma PDX in mouse models and in canine osteosarcoma tumors
- Sharayu Karkare
- , Kevin J. H. Allen
- & Ekaterina Dadachova
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| Open AccessUrinary miRNA-27b-3p and miRNA-1228-3p correlate with the progression of Kidney Fibrosis in Diabetic Nephropathy
- Francesca Conserva
- , Mariagrazia Barozzino
- & Loreto Gesualdo
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| Open AccessA simple method for evaluation pharmacokinetics of glycyrrhetinic acid and potential drug-drug interaction between herbal ingredients
- Neng Zhou
- , Caiyuan Zou
- & Jiayi Huang
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| Open AccessNiclosamide reverses adipocyte induced epithelial-mesenchymal transition in breast cancer cells via suppression of the interleukin-6/STAT3 signalling axis
- Jones Gyamfi
- , Yun-Hee Lee
- & Junjeong Choi
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| Open AccessLow immunogenic endothelial cells endothelialize the Left Ventricular Assist Device
- Constanca Figueiredo
- , Dorothee Eicke
- & Bettina Wiegmann
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| Open AccessThe interleukin-33-mediated inhibition of expression of two key genes implicated in atherosclerosis in human macrophages requires MAP kinase, phosphoinositide 3-kinase and nuclear factor-κB signaling pathways
- Melanie L. Buckley
- , Jessica O. Williams
- & Dipak P. Ramji
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| Open AccessAn immortalized cell line derived from renal erythropoietin-producing (REP) cells demonstrates their potential to transform into myofibroblasts
- Koji Sato
- , Ikuo Hirano
- & Norio Suzuki
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| Open AccessComparing human iPSC-cardiomyocytes versus HEK293T cells unveils disease-causing effects of Brugada mutation A735V of NaV1.5 sodium channels
- Jeanne de la Roche
- , Paweorn Angsutararux
- & Robert Zweigerdt
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| Open AccessEstablishment of a Murine Pro-acinar Cell Line to Characterize Roles for FGF2 and α3β1 Integrins in Regulating Pro-acinar Characteristics
- Renée F. Thiemann
- , Deirdre A. Nelson
- & Susan E. LaFlamme
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| Open AccessWhite LED Light Exposure Inhibits the Development and Xanthophore Pigmentation of Zebrafish Embryo
- Ünsal Veli Üstündağ
- , E. Çalıskan-Ak
- & Ebru Emekli-Alturfan
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| Open AccessRelationships of Non-coding RNA with diabetes and depression
- Tian An
- , Jing Zhang
- & Guang-Jian Jiang
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| Open AccessImage quality evaluation in a modern PET system: impact of new reconstructions methods and a radiomics approach
- Gabriel Reynés-Llompart
- , Aida Sabaté-Llobera
- & Cristina Gámez-Cenzano
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| Open AccessAnticancer properties of 5Z-(4-fluorobenzylidene)-2-(4-hydroxyphenylamino)-thiazol-4-one
- Konrad A. Szychowski
- , Danylo V. Kaminskyy
- & Jan Gmiński
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| Open AccessEffect of antioxidants on BPA-induced stress on sperm function in a mouse model
- Md Saidur Rahman
- , Kyu-Ho Kang
- & Myung-Geol Pang
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| Open AccessNovel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies
- Tim Pieters
- , Sara T’Sas
- & Pieter Van Vlierberghe
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| Open AccessDistinct epigenetic profiles in children with perinatally-acquired HIV on antiretroviral therapy
- Stephanie Shiau
- , Renate Strehlau
- & Louise Kuhn
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| Open AccessMolecular alterations and PD-L1 expression in non-ampullary duodenal adenocarcinoma: Associations among clinicopathological, immunophenotypic and molecular features
- Jiro Watari
- , Seiichiro Mitani
- & Hiroto Miwa
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| Open AccessAnalysis of lncRNA-miRNA-mRNA Interactions in Hyper-proliferative Human Pulmonary Arterial Smooth Muscle Cells
- Mahendran Chinnappan
- , Sumedha Gunewardena
- & Navneet K. Dhillon
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| Open AccessSex-, feeding-, and circadian time-dependency of P-glycoprotein expression and activity - implications for mechanistic pharmacokinetics modeling
- Alper Okyar
- , Swati A. Kumar
- & Annabelle Ballesta
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| Open AccessSystematic Review of Somatic Mutations in Splenic Marginal Zone Lymphoma
- Carolina Jaramillo Oquendo
- , Helen Parker
- & Jonathan C. Strefford
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| Open AccessChanges in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress
- Tiia A. Turunen
- , Thomas C. Roberts
- & Mikko P. Turunen
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| Open AccessA Naturally Occurring Splice Variant of GGA1 Inhibits the Anterograde Post-Golgi Traffic of α2B-Adrenergic Receptor
- Maoxiang Zhang
- , Xin Xu
- & Guangyu Wu
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| Open AccessHypoxia-induced epithelial-mesenchymal transition and fibrosis for the development of breast capsular contracture
- Yao-Lung Kuo
- , I-Ming Jou
- & Ting-Mao Chou
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| Open AccessA 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4
- Paul R. Gilson
- , Rasika Kumarasingha
- & Belinda M. Abbott
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| Open AccessSDHC epi-mutation testing in gastrointestinal stromal tumours and related tumours in clinical practice
- Ruth T. Casey
- , Rogier ten Hoopen
- & Eamonn R. Maher
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| Open AccessGenotype-phenotype association analysis identifies the role of α globin genes in modulating disease severity of β thalassaemia intermedia in Sri Lanka
- Shiromi Perera
- , Angela Allen
- & Anuja Premawardhena
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| Open AccessThe β2-adrenergic receptor antagonist ICI-118,551 blocks the constitutively activated HIF signalling in hemangioblastomas from von Hippel-Lindau disease
- A. M. Cuesta
- , V. Albiñana
- & L. M. Botella
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| Open AccessThe Application of Ultrasonic Vibration in Human Sperm Cryopreservation as a Novel Method for the Modification of Physicochemical Characteristics of Freezing Media
- Gholami Dariush
- , Riazi Gholamhossein
- & Alaei Loghman
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| Open AccessAssociation between Copy Number Variation and Response to Social Skills Training in Autism Spectrum Disorder
- Kristiina Tammimies
- , Danyang Li
- & Sven Bölte
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| Open AccessReproduction of molecular subtypes of gastric adenocarcinoma by transcriptome sequencing of archival tissue
- You Jeong Heo
- , Charny Park
- & Kyoung-Mee Kim
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| Open AccessPro-inflammatory role of NLRP3 inflammasome in experimental sterile corneal inflammation
- Hiroaki Shimizu
- , Tohru Sakimoto
- & Satoru Yamagami
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| Open AccessMicroRNA profiling and identification of let-7a as a target to prevent chemotherapy-induced primordial follicles apoptosis in mouse ovaries
- C. Alexandri
- , B. Stamatopoulos
- & I. Demeestere
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| Open AccessImpaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency
- Magnhild E. Macpherson
- , Bente Halvorsen
- & Silje F. Jørgensen
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| Open AccessUnusual Flavones from Primula macrocalyx as Inhibitors of OAT1 and OAT3 and as Antifungal Agents against Candida rugosa
- Xue Li
- , Xue Wang
- & Robert P. Borris
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| Open AccessA novel potent autophagy inhibitor ECDD-S27 targets vacuolar ATPase and inhibits cancer cell survival
- Jiraporn Paha
- , Phongthon Kanjanasirirat
- & Marisa Ponpuak
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| Open AccessgH625-liposomes as tool for pituitary adenylate cyclase-activating polypeptide brain delivery
- Giuseppina Iachetta
- , Annarita Falanga
- & Salvatore Valiante
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| Open AccessIdentification of small molecule enzyme inhibitors as broad-spectrum anthelmintics
- Rahul Tyagi
- , Mostafa A. Elfawal
- & Makedonka Mitreva
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| Open AccessPharmacologic targeting of β-catenin improves fracture healing in old mice
- Yoon Hae Kwak
- , Tomasa Barrientos
- & Benjamin A. Alman
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| Open AccessYeast screening system reveals the inhibitory mechanism of cancer cell proliferation by benzyl isothiocyanate through down-regulation of Mis12
- Naomi Abe-Kanoh
- , Narumi Kunisue
- & Yoshimasa Nakamura
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| Open AccessOrobol, an Enzyme-Convertible Product of Genistein, exerts Anti-Obesity Effects by Targeting Casein Kinase 1 Epsilon
- Hee Yang
- , Sang‐Hyuk Lee
- & Ki Won Lee
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| Open AccessHigh-Resolution Copy Number Patterns From Clinically Relevant FFPE Material
- Anastasia Filia
- , Alastair Droop
- & D. Timothy Bishop
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| Open AccessSevere pulmonary disease in an adult primary ciliary dyskinesia population in Brazil
- Mary Anne Kowal Olm
- , Fernando Augusto Lima Marson
- & Thais Mauad
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| Open AccessContribution of DNA methylation to the expression of FCGRT in human liver and myocardium
- R. B. Cejas
- , D. C. Ferguson
- & J. G. Blanco