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Article
| Open AccessLandscape of transcriptome variations uncovering known and novel driver events in colorectal carcinoma
- Giovanna Pira
- , Paolo Uva
- & Maria Rosaria De Miglio
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Article
| Open AccessIncreased 18F-FDG signal recovery from small physiological structures in digital PET/CT and application to the pituitary gland
- Marie Meyer
- , Gilles Allenbach
- & Silvano Gnesin
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Article
| Open AccessReinterpretation of common pathogenic variants in ClinVar revealed a high proportion of downgrades
- Jiale Xiang
- , Jiyun Yang
- & Zhiyu Peng
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Article
| Open AccessEnhancement of FAK alleviates ventilator-induced alveolar epithelial cell injury
- Mingxing Fang
- , Na Liu
- & Zhiyong Wang
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Article
| Open AccessHyaluronan suppresses enhanced cathepsin K expression via activation of NF-κB with mechanical stress loading in a human chondrocytic HCS-2/8 cells
- Mochihito Suzuki
- , Nobunori Takahashi
- & Toshihisa Kojima
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Article
| Open AccessThe ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness
- Liselot M. Mus
- , Irina Lambertz
- & Frank Speleman
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Article
| Open AccessTranscriptional analysis identifies potential biomarkers and molecular regulators in pneumonia and COPD exacerbation
- Wilhelm Bertrams
- , Kathrin Griss
- & Bernd Schmeck
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Article
| Open AccessAntioxidant Activities of an Exopolysaccharide (DeinoPol) Produced by the Extreme Radiation-Resistant Bacterium Deinococcus radiodurans
- Shun Mei Lin
- , Chan Yu Baek
- & Sangyong Lim
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Article
| Open AccessVisualization of mucosal field in HPV positive and negative oropharyngeal squamous cell carcinomas: combined genomic and radiology based 3D model
- Eva Orosz
- , Katalin Gombos
- & Istvan Szanyi
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Article
| Open AccessOral administration of EP4-selective agonist KAG-308 suppresses mouse knee osteoarthritis development through reduction of chondrocyte hypertrophy and TNF secretion
- Yasutaka Murahashi
- , Fumiko Yano
- & Taku Saito
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Article
| Open AccessSpecific role of N-methyl-D-aspartate (NMDA) receptor in elastin-derived VGVAPG peptide-dependent calcium homeostasis in mouse cortical astrocytes in vitro
- Konrad A. Szychowski
- & Jan Gmiński
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Article
| Open AccessDifferential IL-17A response to S. pneumoniae in adenoid tissue of children with sleep disordered breathing and otitis media with effusion
- Chien-Chia Huang
- , Pei-Wen Wu
- & Cheng-Hsun Chiu
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Article
| Open AccessMaintenance of Deep Lung Architecture and Automated Airway Segmentation for 3D Mass Spectrometry Imaging
- Alison J. Scott
- , Courtney E. Chandler
- & Robert K. Ernst
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Article
| Open AccessMycobacterium tuberculosis clinical isolates of the Beijing and East-African Indian lineage induce fundamentally different host responses in mice compared to H37Rv
- Bas C. Mourik
- , Jurriaan E. M. de Steenwinkel
- & Pieter J. M. Leenen
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Article
| Open AccessRecombinant HIV-1 vaccine candidates based on replication-defective flavivirus vector
- M. Giel-Moloney
- , M. Esteban
- & K. V. Pugachev
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Article
| Open AccessSmall molecule allosteric uncoupling of microtubule depolymerase activity from motility in human Kinesin-5 during mitotic spindle assembly
- Catherine D. Kim
- , Elizabeth D. Kim
- & Edward J. Wojcik
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Article
| Open AccessDatabase of adverse events associated with drugs and drug combinations
- Aleksandar Poleksic
- & Lei Xie
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Article
| Open AccessProteomic and Transcriptomic Changes in Hibernating Grizzly Bears Reveal Metabolic and Signaling Pathways that Protect against Muscle Atrophy
- D. A. Mugahid
- , T. G. Sengul
- & M. Gotthardt
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Article
| Open AccessCALR mutations in a cohort of JAK2 V617F negative patients with suspected myeloproliferative neoplasms
- Tanja Belcic Mikic
- , Tadej Pajic
- & Matjaz Sever
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Article
| Open Accessβ-catenin signaling inhibitors ICG-001 and C-82 improve fibrosis in preclinical models of endometriosis
- Tomoko Hirakawa
- , Kaei Nasu
- & Hisashi Narahara
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Article
| Open AccessIdentification of miR-328-3p as an endogenous reference gene for the normalization of miRNA expression data from patients with Diabetic Retinopathy
- Marcelle SanJuan Ganem Prado
- , Thaline Cunha de Goes
- & Carla Martins Kaneto
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Article
| Open AccessCaveolin-1 gene therapy inhibits inflammasome activation to protect from bleomycin-induced pulmonary fibrosis
- Xin Lin
- , Michael Barravecchia
- & David A Dean
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Article
| Open AccessSlow Freezing Versus Vitrification of Mouse Ovaries: from Ex Vivo Analyses to Successful Pregnancies after Auto-Transplantation
- Carmen Terren
- , Maïté Fransolet
- & Carine Munaut
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Article
| Open AccessPrecision cancer monitoring using a novel, fully integrated, microfluidic array partitioning digital PCR platform
- Megan E. Dueck
- , Robert Lin
- & Elliot Stieglitz
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Article
| Open AccessJatrorrhizine Balances the Gut Microbiota and Reverses Learning and Memory Deficits in APP/PS1 transgenic mice
- Sheng Wang
- , Wei Jiang
- & Hua-Qiao Wang
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Article
| Open AccessNeuronal and perineuronal changes of cerebral cortex after exposure to inhaled particulate matter
- So Young Kim
- , Da-hye Lee
- & Moo Kyun Park
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Article
| Open AccessRepotrectinib (TPX-0005), effectively reduces growth of ALK driven neuroblastoma cells
- Diana Cervantes-Madrid
- , Joanna Szydzik
- & Bengt Hallberg
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Article
| Open AccessGIRK1 triggers multiple cancer-related pathways in the benign mammary epithelial cell line MCF10A
- Gebhard Schratter
- , Susanne Scheruebel
- & Wolfgang Schreibmayer
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Article
| Open AccessModulation of the leptin receptors expression in breast cancer cell lines exposed to leptin and tamoxifen
- Rodolfo López Linares
- , Jonnathan Guadalupe Santillán Benítez
- & Antonio Sandoval-Cabrera
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Article
| Open AccessOral Microbiota Development in Early Childhood
- Beatrice Kennedy
- , Sari Peura
- & Tove Fall
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Article
| Open AccessCharacterization of the enzymatic activity of the serine protease domain of Factor VII activating protease (FSAP)
- Nis V. Nielsen
- , Elfie Roedel
- & Sandip M. Kanse
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Article
| Open AccessComparative proteomics reveals unexpected quantitative phosphorylation differences linked to platelet activation state
- G. J. Schmidt
- , C. M. Reumiller
- & M. Zellner
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Article
| Open AccessSystemic inhibition of tissue-nonspecific alkaline phosphatase alters the brain-immune axis in experimental sepsis
- Allison L. Brichacek
- , Stanley A. Benkovic
- & Candice M. Brown
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Article
| Open AccessNanoparticle Contrast-enhanced T1-Mapping Enables Estimation of Placental Fractional Blood Volume in a Pregnant Mouse Model
- Andrew A. Badachhape
- , Laxman Devkota
- & Ketan B. Ghaghada
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Article
| Open AccessFirst identification of mammalian orthoreovirus type 3 by gut virome analysis in diarrheic child in Brazil
- Ulisses Alves Rosa
- , Geovani de Oliveira Ribeiro
- & Élcio Leal
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Article
| Open AccessRefinement of evolutionary medicine predictions based on clinical evidence for the manifestations of Mendelian diseases
- Daniela Šimčíková
- & Petr Heneberg
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Article
| Open AccessDAXX mutations as potential genomic markers of malignant evolution in small nonfunctioning pancreatic neuroendocrine tumors
- Mauro Cives
- , Stefano Partelli
- & Franco Silvestris
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Article
| Open AccessDNA methylation of a NF-κB binding site in the aquaporin 5 promoter impacts on mortality in sepsis
- Katharina Rump
- , Matthias Unterberg
- & Tim Rahmel
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Article
| Open AccessThe Role and Mechanism of SIRT1 in Resveratrol-regulated Osteoblast Autophagy in Osteoporosis Rats
- Xuhao Yang
- , Tianlong Jiang
- & Lei Guo
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Article
| Open AccessMultiple sclerosis drug FTY-720 toxicity is mediated by the heterotypic fusion of organelles in neuroendocrine cells
- Yolanda Gimenez-Molina
- , Virginia García-Martínez
- & Luis M. Gutiérrez
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Article
| Open AccessOxytocin maintains lung histological and functional integrity to confer protection in heat stroke
- Cheng-Hsien Lin
- , Cheng-Chia Tsai
- & Hsi-Hsing Yang
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Article
| Open AccessStructural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension
- Apirat Chaikuad
- , Chancievan Thangaratnarajah
- & Alex N. Bullock
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Article
| Open AccessSphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation
- Kazuhiro Ishimaru
- , Kazuaki Yoshioka
- & Yoh Takuwa
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Article
| Open AccessLoss of the serine protease HTRA1 impairs smooth muscle cells maturation
- Ralph Klose
- , Alexander Prinz
- & Andreas Fischer
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Article
| Open AccessUpregulation of vitamin D-binding protein is associated with changes in insulin production in pancreatic beta-cells exposed to p,p′-DDT and p,p′-DDE
- Nela Pavlíková
- , Petr Daniel
- & Jan Kovář
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Article
| Open AccessOPN promotes the aggressiveness of non-small-cell lung cancer cells through the activation of the RON tyrosine kinase
- Chengcheng Hao
- , Yuxin Cui
- & Wen G. Jiang
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Article
| Open AccessPrognostic classification of endometrial cancer using a molecular approach based on a twelve-gene NGS panel
- Raquel López-Reig
- , Antonio Fernández-Serra
- & José Antonio López-Guerrero
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Article
| Open AccessLandscape of heart proteome changes in a diet-induced obesity model
- Danielle F. Vileigas
- , Victoria M. Harman
- & Antonio C. Cicogna
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Article
| Open AccessGermline de novo variants in CSNK2B in Chinese patients with epilepsy
- Jinliang Li
- , Kai Gao
- & Yuwu Jiang