HIV infections articles from across Nature Portfolio

HIV infections (human immunodeficiency virus infections) include the spectrum of infections caused by the virus HIV that range from asymptomatic seropositivity to acquired immunodeficiency syndrome (AIDS)-related complex (ARC) and AIDS.

Featured

News & Views | 27 February 2023

HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Nature Medicine, 1-2

Latest Research and Reviews

Research
21 March 2023 | Open Access

Acute antagonism in three-drug combinations for vaginal HIV prevention in humanized mice
- Philippe A. Gallay
- , Christina M. Ramirez
- & Marc M. Baum
Scientific Reports 13, 4594
Research | 21 March 2023

Prognostic effect of HIV on visual acuity in ocular syphilis: a systematic review
- Laura Z. Wu
- , Tatiana M. Orlowski
- & Lulu L. C. D. Bursztyn
Eye, 1-11
Research
14 March 2023 | Open Access

Antiretroviral therapy regimen modification rates and associated factors in a cohort of HIV/AIDS patients in Asmara, Eritrea: a 16-year retrospective analysis
- Samuel Tekle Mengistu
- , Arsema Yohannes
- & Saleem Basha
Scientific Reports 13, 4183
Research
07 March 2023 | Open Access

Direct intranodal tonsil vaccination with modified vaccinia Ankara vaccine protects macaques from highly pathogenic SIVmac251

Mucosal surfaces are a primary route of HIV entry, yet the compartmentalisation between mucosal and peripheral immune systems remain a challenge for HIV vaccine candidates. Authors utilise a combination of intranodal tonsil MALT and systemic vaccination in the rhesus macaque model to explore immune responses and protection from highly pathogenic simian homologue of HIV.
- Jeffy G. Mattathil
- , Asisa Volz
- & Joseph J. Mattapallil
Nature Communications 14, 1264
Research
02 March 2023 | Open Access

Autologous dendritic cell vaccination against HIV-1 induces changes in natural killer cell phenotype and functionality
- Thessa Laeremans
- , Sabine den Roover
- & Joeri L. Aerts
npj Vaccines 8, 29
Research
27 February 2023 | Open Access

Phenotypic characterization of single CD4+ T cells harboring genetically intact and inducible HIV genomes

Some HIV-infected cells persist during antiretroviral therapies (ART) but their phenotype is less clear. Dufour et al. show that HIV-infected cells that persist in people receiving ART are phenotypically diverse and that CD4+ T cells expressing the integrin VLA-4 are highly enriched in replication-competent HIV.
- Caroline Dufour
- , Corentin Richard
- & Nicolas Chomont
Nature Communications 14, 1115

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News and Comment

News & Views | 27 February 2023

HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

We describe a 53-year-old man with HIV-1 who received allogeneic CCR5Δ32/Δ32 hematopoietic stem cell transplantation (HSCT) in 2013 to treat acute myeloid leukemia. Four years after analytic treatment interruption (ATI), the absence of viral rebound and the lack of immunological correlates of HIV-1 antigen persistence provide convincing evidence for HIV-1 cure.

Nature Medicine, 1-2
News | 21 February 2023

Third patient free of HIV after receiving virus-resistant cells

But the risks associated with the procedure mean it is unlikely to be used widely in its current form.
- Sara Reardon
Nature 615, 13-14
Research Highlights | 08 November 2022

USPSTF reaffirms recommendations on screening for syphilis infection
- Louise Stone
Nature Reviews Urology 19, 693
Editorial | 05 October 2022

Laggard rich countries risk slowing the fight against AIDS, malaria and TB

The United Kingdom and Italy need to renew their commitments to banish these major infectious killers from the world.

Nature 610, 8
Research Highlights | 04 October 2022

Long-acting ART in poor viral suppression
- Annette Fenner
Nature Reviews Urology 19, 634
Research Highlights | 23 August 2022

Isotype matters
- Laurie A. Dempsey
Nature Immunology 23, 1292

All News & Comment

HIV infections articles from across Nature Portfolio

Featured

HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Latest Research and Reviews

Acute antagonism in three-drug combinations for vaginal HIV prevention in humanized mice

Prognostic effect of HIV on visual acuity in ocular syphilis: a systematic review

Antiretroviral therapy regimen modification rates and associated factors in a cohort of HIV/AIDS patients in Asmara, Eritrea: a 16-year retrospective analysis

Direct intranodal tonsil vaccination with modified vaccinia Ankara vaccine protects macaques from highly pathogenic SIVmac251

Autologous dendritic cell vaccination against HIV-1 induces changes in natural killer cell phenotype and functionality

Phenotypic characterization of single CD4+ T cells harboring genetically intact and inducible HIV genomes

News and Comment

HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Third patient free of HIV after receiving virus-resistant cells

USPSTF reaffirms recommendations on screening for syphilis infection

Laggard rich countries risk slowing the fight against AIDS, malaria and TB

Long-acting ART in poor viral suppression

Isotype matters

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