Gene targeting articles within Nature Reviews Cardiology

Featured

• Research Highlight | 24 January 2023

  Base editing of CaMKIIδ shows promise as cardiac therapy

  CRISPR–Cas9 base editing of the oxidative activation sites of CaMKIIδ protects the heart from ischaemia–reperfusion damage in mice.

  • Irene Fernández-Ruiz

• Research Highlight | 11 February 2020

  New developments in gene editing for Duchenne muscular dystrophy

  A somatic gene editing therapy for the treatment of Duchenne muscular dystrophy (DMD) improves skeletal and cardiac muscle function and reduces cardiac arrhythmogenic vulnerability in a pig model of DMD and an in vitro model of human DMD.

  • Irene Fernández-Ruiz