Featured
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Correspondence |
Cancer, obesity, and diabetes: TKIs exert multiple effects on glucose homeostasis
- Michael N. Pollak
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Correspondence |
Cancer, obesity, and diabetes: TKIs exert multiple effects on glucose homeostasis
- Minglin Lin
- & Junfei Jin
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Review Article |
Cancer, obesity, diabetes, and antidiabetic drugs: is the fog clearing?
The prevalence rates of obesity, type 2 diabetes mellitus, and cancer are increasing globally. Herein, the relationships between these diseases and their treatments are reviewed, and the practical principles relevant to the increasingly common challenge of managing patients who have been diagnosed with both diabetes and cancer are outlined.
- Adi J. Klil-Drori
- , Laurent Azoulay
- & Michael N. Pollak
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Review Article |
Clinical management of obese patients with cancer
Evidence links obesity to increased cancer incidence, and possibly also to poorer cancer survival. Obese patients face a range of specific challenges related to the diagnosis and treatment of cancer. This Review summarizes the available literature addressing the clinical management of obese patients with cancer and discusses opportunities to improve the cancer care of these patients.
- Wenjing Tao
- & Jesper Lagergren
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Review Article |
Chemotherapy dosing in overweight and obese patients with cancer
Evidence indicates that reductions in recommended doses of chemotherapy often occur among obese patients with cancer. ASCO guidelines recommend that chemotherapy dosing in obese patients should be calculated based on actual weight, rather than the current practice based on estimation of body surface area. In this Review, chemotherapy dosing in this population is discussed along with how future research could lead to a more-personalized approach.
- Gary H. Lyman
- & Alex Sparreboom
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News & Views |
Diabetes risk after radiation—not out of the woods
A retrospective cohort study has shown that pancreatic radiation is a risk factor for diabetes in survivors of paediatric cancer. This validates and refines prior epidemiological observations of diabetes after radiation to the abdomen and total-body irradiation, and will result in modification of surveillance recommendations in national survivor guidelines.
- Lillian R. Meacham
- & Kimberley J. Dilley
Cardiovascular events linked to levels of cortisol production
Gut microbiota feeds obesity-induced liver cancer
Cachexia—skeletal muscle depletion is a prognostic factor