Diffusion tensor imaging articles from across Nature Portfolio

Whether connectivity in white matter detected by functional MRI relates to underlying electrophysiological synchronization is unclear. Here, the authors show that blood-oxygenation-level-dependent (BOLD) functional connectivity and intracranial stereotactic-electroencephalography (SEEG) connectivity are correlated across a wide range of frequency bands.

In gray matter, the relative contributions of myelinated axons and other tissue features to diffusion MRI (dMRI) are poorly understood. Here the authors combine ex vivo high-resolution dMRI of marmoset brain with histological sections of the same brain, and their findings suggest that in cortex, dMRI does not match the spatial distribution of myelin in the gray matter.

Characterizing the brain’s connectome at multiple scales is essential for unraveling fundamental principles of cortical information processing and how it impacts behavior. A GPU-based implementation for connectome pruning is proposed, achieving greater than 100-fold speedups over previous CPU-based implementations.