Chemotherapy articles within Nature Reviews Cardiology

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  • News & Views |

    The renin–angiotensin system is thought to have a key role in the structural remodeling of the left ventricle that accompanies healing after acute myocardial infarction and is an important determinant of long-term prognosis. Does a direct renin inhibitor provide additive benefit to patients already treated with β-blockers and either angiotensin-converting-enzyme inhibitors or angiotensin-receptor blockers?

    • Jay N. Cohn

  • News & Views |

    A network meta-analysis by Trelle and colleagues has confirmed that the routine use of all nonsteroidal anti-inflammatory drugs, both nonselective and selective, is associated with an increased risk of cardiovascular events. Although a rigorous method was used in this analysis, comparative safety research in which data from randomized clinical trials is used has some important strengths and weaknesses to consider.

    • Seo Young Kim
    •  & Daniel H. Solomon

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