Cell polarity

Cell polarity is the asymmetric organisation of several cellular components, including its plasma membrane, cytoskeleton or organelles. This asymmetry can be used for specialised functions, such as maintaining a barrier within an epithelium or transmitting signals in neurons.

Latest Research and Reviews

News and Comment

  • News & Views |

    Polar cell growth requires spatiotemporal regulation of Rho of plants (ROPs) small G proteins in membrane domains. In addition to localized activation of membrane-anchored ROPs, a mechanism for their local inactivation has now been identified.

    • Gil Feiguelman
    •  & Shaul Yalovsky
    Nature Plants 6, 1201-1202
  • News & Views |

    Functional single-cell liver hemi-canaliculi have been generated in a synthetic microenvironment using a reductionist approach. It is shown that the interaction between the extracellular matrix and static cadherin is sufficient to develop an apicobasal polarity independently of the contact with neighbouring cells.

    • Covadonga Díaz-Díaz
    •  & Fernando Martín-Belmonte
    Nature Materials 19, 935-937
  • Research Highlights |

    In this Journal Club, Audrey Williams and Sally Horne-Badovinac highlight the importance of studying the basal cell surface and its dynamics to understand epithelial cell behaviours and tissue rearrangements.

    • Audrey M. Williams
    •  & Sally Horne-Badovinac