Bacterial genetics

Bacterial genetics is the study of the mechanisms of heritable information in bacteria, their chromosomes, plasmids, transposons and phages. Techniques that have enabled this discipline are culture in defined media, replica plating, mutagenesis, transformation, conjugation and transduction.

Latest Research and Reviews

News and Comment

  • News and Views |

    Clinicians have long observed that infections diagnosed as susceptible to antibiotics can sometimes resist treatment. New studies show that such treatment failures can be explained by subpopulations of transiently resistant cells that are often missed by standard clinical diagnostics, offering new therapeutic avenues.

    • Viktória Lázár
    •  & Roy Kishony
    Nature Microbiology 4, 1606-1607
  • News and Views |

    Differences in microbial genomes can result in vastly different phenotypes and functions. Consequently, it is critical to understand the genome variations that differentiate microbial strains. Here, we discuss recent exciting advances that enable structural variant measurement, their associated phenotypes and the horizon for future discovery.

    • Matthew G. Durrant
    •  & Ami S. Bhatt
    Nature Microbiology 4, 912-913
  • Research Highlights |

    This study analysed the proportion of uncultured bacteria and archaea globally and found that the majority of environments are dominated by uncultured cells.

    • Ursula Hofer
  • News and Views |

    Widespread use of antibiotics in animals either as growth promoters or for metaphylaxis may drive the spread of clinically relevant drug resistance genes and pathogens. New work uncovers drug resistance gene patterns from livestock across European farms and finds a correlation with agricultural antibiotic use.

    • Timothy R. Walsh
    Nature Microbiology 3, 854-855