In a study reported by Fujiogi et al., infants hospitalized with bronchiolitis were grouped according to coronavirus genus, and their metabolites were analyized. The two groups differed little in clinical manifestations, but they had distinct nasopharyngeal metabolome signatures and nasopharyngeal microbiota profiles.See article by Fujiogi et al. on page 1594.

Illustration done by middle-school students in our first science project for kids. The students reinterpreted the article by Zhang et al., a systematic review on physical therapy in asthma, for their peers. See the article by Ola EL-Khuffash et al. on page 1580.

Expression of stage-specific embryonic antigen-1, a marker of pulmonary stem cells, in respiratory distress syndrome, bronchopulmonary dysplasia, and healthy term lung.See the article by Chaubey et al. on page 1126.

Cerebral cross-channels hemodynamics illustrating regional differences between patients with and without neonatal encephalopathy.See the article by Tian et al. on page 882.

Linkage disequilibrium map of 12 single-nucleotide polymorphisms (SNPs) from the NSD1 region in a Han Chinese population. Yu et al. investigated the relationship between these SNPs and susceptibility to Hirschsprung’s disease. See the article by Yu et al. on page 698.

The image illustrates interactions of social and physical environments with human biology.

Tree maps illustrating T cell receptor gamma phenotypic differences between pediatric heart-surgery patients with and without Down syndrome.See the article by Sun et al. on page 46.