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New research indicates that in a mouse model of Parkinson disease, α-synuclein is trafficked from the brain to the gut by CD11c-expressing macrophages.
Speaking at the XXVI World Congress of Neurology, Eva Feldman highlighted the global burden of diabetic peripheral neuropathy in people with type 2 diabetes and suggested dietary and lifestyle modifications that might help to reduce this burden.
Researchers in China and South Korea have developed a rapid immunodot assay to detect aquaporin 4-targeting IgG autoantibodies in the serum of individuals with neuromyelitis optica spectrum disorder.
Two new studies have provided important mechanistic insights into TDP-43 pathology, a hallmark of neurodegenerative conditions such as amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
A new study identifies LONRF2 as a protein quality control ubiquitin ligase that is induced in senescent neurons and seems to protect them against degeneration
Researchers in China have developed a functional nucleic acid-based responsive artificial enzyme that enables continuous production of levodopa in a mouse model of Parkinson disease.
A new study indicates loss of hypothalamic melanin-concentrating hormone in ALS, providing insights into the mechanisms underlying weight loss in individuals with the disease.