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A new study provides mechanistic insights into the role of TDP43 in regulating the expression of stathmin 2 — a protein that is abundant in motor neurons and is required for axonal regeneration after injury.
According to new research in a mouse model, systemic immune exhaustion could underlie the association between obesity and risk of developing Alzheimer disease.
New research reports changes in serum blood–brain barrier (BBB) markers after bilateral tonic–clonic seizures, corroborating earlier observations in animal models.
A new study reports upregulation of pro-inflammatory cytokines and neurotrophic factors in the cerebrospinal fluid of individuals with a severe form of spinal muscular atrophy.
A genetic variant of the WNT receptor LRP6 exacerbates synapse degeneration in mouse models of ageing and Alzheimer’s disease, according to new research.
In a new study, targeted editing of the epigenome was found to reactivate silenced MECP2 in human embryonic stem cells, suggesting that a similar approach could be used to treat Rett syndrome in girls.