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Acute renal infarction from a cardiac thrombus

Abstract

Background A 53-year-old man presented to hospital 2 hours after the abrupt onset of left upper abdominal pain. He was treated with analgesics and discharged after 4 hours of observation, but presented to another hospital 2 hours later with severe left abdominal pain. His past medical history included ischemic dilated cardiomyopathy due to recurrent myocardial infarction.

Investigations Physical examination, electrocardiography, laboratory investigations, contrast-enhanced computed tomography, and transesophageal echocardiography.

Diagnosis Renal artery thromboembolism resulting from dilated cardiomyopathy, severely reduced cardiac function and an intracardiac thrombus.

Management Anticoagulation with unfractionated heparin followed by enoxaparin and warfarin.

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Figure 1: Axial contrast-enhanced computed tomography image of the patient's abdomen with maximal intensity projection reconstruction.
Figure 2: Transesophageal echocardiogram showing the severely enlarged left atrium and ventricle.
Figure 3: Contrast-enhanced computed tomography images of the patient's abdomen on his second admission to hospital, with maximal intensity projection reconstruction.

References

  1. Fatkin D et al. (1994) Relations between left atrial appendage blood flow velocity, spontaneous echocardiographic contrast and thromboembolic risk in vivo. J Am Coll Cardiol 23: 961–969

    Article  CAS  Google Scholar 

  2. González-Torrecilla E et al. (2000) Predictors of left atrial spontaneous echo contrast and thrombi in patients with mitral stenosis and atrial fibrillation. Am J Cardiol 86: 529–534

    Article  Google Scholar 

  3. Martinelli I (2005) von Willebrand factor and factor VIII as risk factors for arterial and venous thrombosis. Semin Hematol 42: 49–55

    Article  CAS  Google Scholar 

  4. Lin HY et al. (2007) Misleadingly migratory pain in acute renal infarction. Am J Emerg Med 25: 237–239

    Article  Google Scholar 

  5. Huang CC et al. (2007) ED presentations of acute renal infarction. Am J Emerg Med 25: 164–169

    Article  Google Scholar 

  6. Korzets Z et al. (2002) The clinical spectrum of acute renal infarction. Isr Med Assoc J 4: 781–784

    PubMed  Google Scholar 

  7. Ergun I et al. (2007) Acute renal infarction in a heavy smoker. Int Urol Nephrol 39: 951–954

    Article  Google Scholar 

  8. Davutoglu V et al. (2005) Renal infarction mimicking renal colic in patient with a prosthetic aortic valve. Emerg Med J 22: 595–596

    Article  CAS  Google Scholar 

  9. Majumdar A et al. (2000) Renal pathological findings in infective endocarditis. Nephrol Dial Transplant 15: 1782–1787

    Article  CAS  Google Scholar 

  10. Edoute Y et al. (1997) Cardiac valvular vegetations in cancer patients: a prospective echocardiographic study of 200 patients. Am J Med 102: 252–258

    Article  CAS  Google Scholar 

  11. Fujisaki K et al. (2007) Acute renal infarction in a patient with left atrial myxoma. Clin Nephrol 67: 53–57

    Article  CAS  Google Scholar 

  12. Bemanian S et al. (2005) Cocaine-induced renal infarction: report of a case and review of the literature. BMC Nephrol 6: 10

    Article  Google Scholar 

  13. Bolderman R et al. (2006) Idiopathic renal infarction. Am J Med 119: 356.e9–356.e12

    Article  Google Scholar 

  14. Chu PL et al. (2006) Clinical characteristics of patients with segmental renal infarction. Nephrology (Carlton) 11: 336–340

    Article  CAS  Google Scholar 

  15. Huang CC et al. (2006) Renal infarction without hematuria: two case reports. J Emerg Med 30: 57–61

    Article  Google Scholar 

  16. Hazanov N et al. (2004) Acute renal embolism: forty-four cases of renal infarction in patients with atrial fibrillation. Medicine (Baltimore) 83: 292–299

    Article  Google Scholar 

  17. Tsai SH et al. (2007) Acute renal infarction: a 10-year experience. Int J Clin Pract 61: 62–67

    Article  Google Scholar 

  18. Domanovits H et al. (1999) Acute renal infarction: clinical characteristics of 17 patients. Medicine (Baltimore) 78: 386–394

    Article  CAS  Google Scholar 

  19. Blum U et al. (1993) Effect of local low-dose thrombolysis on clinical outcome in acute embolic renal artery occlusion. Radiology 189: 549–554

    Article  CAS  Google Scholar 

  20. Nicholas GG and DeMuth WE Jr (1984) Treatment of renal artery embolism. Arch Surg 119: 278–281

    Article  CAS  Google Scholar 

Download references

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Correspondence to Nicola J Nasser.

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The authors declare no competing financial interests.

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Nasser, N., Abadi, S. & Azzam, Z. Acute renal infarction from a cardiac thrombus. Nat Rev Nephrol 3, 631–635 (2007). https://doi.org/10.1038/ncpneph0624

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  • DOI: https://doi.org/10.1038/ncpneph0624

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