Research Highlights in 2017

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  • Chewing induces the accumulation of T helper 17 cells in the mouth.

    • Lucy Bird
    Research Highlight

  • Increased expression of inflammasome-related gene modules in older individuals correlates with nucleotide metabolism dysfunction, IL-1β production and cardiovascular disease.

    • Kirsty Minton
    Research Highlight

  • Plasma cells accumulate in the ageing thymus and may provide protection against viral infections.

    • Yvonne Bordon
    Research Highlight

  • Interleukin-33 is a key driver of type 2 immunity in the developing neonatal lung of mice both in the steady state and in response to allergen exposure.

    • Lydia Shipman
    Research Highlight

  • NLRC3 protects against colorectal cancer by suppressing the proliferation of intestinal epithelial cells through inhibition of the PI3K–AKT–mTOR pathway.

    • Olive Leavy
    Research Highlight