From the Analyst's Couch in 2017

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  • The market for atopic dermatitis therapies is dominated by topical corticosteroids, but is poised to change with the recent approvals of dupilumab and crisaborole, as well as other drugs in clinical development.

    • Eleni Pantazi
    • Gianluca Valenza
    • Bashar Hamad
    From the Analyst's Couch
  • This article discsusses how biomarkers will continue to change the market for non-small-cell lung cancer.

    • Mine Esencay
    • Andrew Watson
    • Steven I. Gubernick
    From the Analyst's Couch
  • This article discusses investment in microbiome-based therapeutic approaches and key questions for the field related to the underlying science, clinical development, regulation and business models.

    • Pedro M. Valencia
    • Magali Richard
    • Elsy Boglioli
    From the Analyst's Couch
  • This analysis of US drug launches from the past decade indicates that commercial success has become more difficult to achieve, owing to factors such as increased competition, greater challenges in achieving therapeutic differentiation and payer pressures.

    • Nicholas Donoghoe
    • Jon Duane
    • George Xu
    From the Analyst's Couch
  • This analysis investigates whether some companies may be negatively affecting their overall commercial success by aiming to maintain steady earnings per share growth and/or a target ratio of R&D spending to sales.

    • Michael S. Ringel
    From the Analyst's Couch
  • This article discusses the impact of new drugs on the market for multiple sclerosis, including the recently approved immunomodulatory drug ocrelizumab and drugs in development such as sphingosine 1-phosphate receptor modulators and neurorestorative agents.

    • Anders Westad
    • Aditya Venugopal
    • Eric Snyder
    From the Analyst's Couch
  • This article discusses the impact of the recent approvals of poly ADP ribose polymerase (PARP) inhibitors on the market for ovarian cancer drugs, as well as potential future treatments such as immunotherapies.

    • Jennifer Bamford
    • Rachel M. Webster
    From the Analyst's Couch
  • This article presents the findings of a recent analysis of the costs of clinical trials, providing benchmark data for companies to assess their performance, as well as indicating cost drivers.

    • Linda Martin
    • Melissa Hutchens
    • Alaina Radnov
    From the Analyst's Couch
  • The market for colorectal cancer therapies, which is currently dominated by drugs targeting vascular endothelial growth factor and epidermal growth factor receptor, is poised for change with the anticipated entry of immunotherapies and other targeted drugs.

    • Sorcha Cassidy
    • Basharut A. Syed
    From the Analyst's Couch
  • This analysis provides an overview of novel antihypertensive products, many of which are fixed-dose combinations of different drug classes, and provides an outlook on their likely impact on the market.

    • M. Adam Ali
    • Salman Rizvi
    • Basharut A. Syed
    From the Analyst's Couch
  • This article analyses merger and acquisition (M&A) activity and partnerships in the biopharma industry in 2016, highlighting trends and major deals.

    • Amanda Micklus
    • Steven Muntner
    From the Analyst's Couch
  • This article analyses the huge volume of clinical trial activity for immune checkpoint inhibitors, and discusses the development of the market and strategic trends for immuno-oncology therapies in general.

    • Stephen Cavnar
    • Pedro Valencia
    • Valery Panier
    From the Analyst's Couch
  • Two PD-1 directed checkpoint inhibitors have recently been approved for squamous cell carcinoma of the head and neck (SCCHN). Further checkpoint inhibitors, as well as other molecularly targeted agents and cytokine-based immunotherapies, are currently in the late-stage pipeline and are poised to change the treatment paradigm for SCCHN.

    • Jennifer Bamford
    • Rachel M. Webster
    From the Analyst's Couch