Review Articles, News & Views, Perspectives, Hypotheses, Analyses and Review in 2002

The use and analysis of microarray data

• Atul Butte

Microbicides: a new approach to preventing HIV and other sexually transmitted infections

• Alan Stone

Dual-specificity phosphatases as targets for antineoplastic agents

• Michael A. Lyon
• Alexander P. Ducruet
• John S. Lazo

Blocking NO synthesis: how, where and why?

• Patrick Vallance
• James Leiper

New therapeutics that antagonize endothelin: promises and frustrations

• Giuseppe Remuzzi
• Norberto Perico
• Ariela Benigni

Hepatitis C therapeutics: current status and emerging strategies

• Seng-Lai Tan
• Arnim Pause
• Nahum Sonenberg

Integration of virtual and high-throughput screening

• Jürgen Bajorath

Designing peptide receptor agonists and antagonists

• Victor J. Hruby

The future challenges facing the development of new antimicrobial drugs

• Anthony Coates
• Yanmin Hu
• Clive Page

Therapeutic strategies for Alzheimer's disease

• Michael S. Wolfe

Toll-like receptors as potential therapeutic targets for multiple diseases

• Claudia Zuany-Amorim
• John Hastewell
• Christoph Walker

Discoveries, drugs and skeletal disorders

• David Goltzman

G-Protein-coupled receptor oligomerization and its potential for drug discovery

• Susan R. George
• Brian F. O'Dowd
• Samuel P. Lee

Putting chirality to work: the strategy of chiral switches

• Israel Agranat
• Hava Caner
• John Caldwell

Structural biology of insulin and IGF1 receptors: implications for drug design

• Pierre De Meyts
• Jonathan Whittaker

ATPases as drug targets: learning from their structure

• Patrick Chène

Clinical proteomics: translating benchside promise into bedside reality

• Emanuel F. Petricoin
• Kathryn C. Zoon
• Lance A. Liotta

Phosphodiesterase 5 inhibitors: current status and potential applications

• David P. Rotella

Protein tyrosine phosphatase 1B inhibitors for diabetes

• Theodore O. Johnson
• Jacques Ermolieff
• Michael R. Jirousek

Pharmacotherapy of addictions

• Mary Jeanne Kreek
• K. Steven LaForge
• Eduardo Butelman