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Heart failure in 2010

One step forward, two steps back

Patients with heart failure (HF) fall into two categories—those who are stable and ambulatory with a relatively low event rate, and patients requiring hospitalization who are characterized by high post-discharge mortality and rates of rehospitalization. HF trials in 2010 contributed to the advancement of outpatient management, whereas the development of novel therapies with a survival benefit remains an unmet need in acute HF syndromes.

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Correspondence to Mihai Gheorghiade.

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Competing interests

M. Gheorghiade has received grants/research support from Bayer, Debiopharm, Medtronic, Novartis, Otsuka, PeriCor, Sigma-Tau, and Solvay Pharmaceuticals; and has been a consultant for Abbott, Astellas, AstraZeneca, Bayer, Corthera, Cytokinetics, Debiopharm, Errekappa Euroterapici, GlaxoSmithKline, Johnson & Johnson, Medtronic, Merck, Novartis, Otsuka, PDL BioPharma, PeriCor, Scios, Sigma-Tau, and Solvay Pharmaceuticals. A. Ambrosy declares no competing interests.

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Gheorghiade, M., Ambrosy, A. One step forward, two steps back. Nat Rev Cardiol 8, 72–73 (2011). https://doi.org/10.1038/nrcardio.2010.205

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