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The prospect of nonsurgical replacement of cardiac valves by percutaneous valve replacement holds immense promise for both patients and clinicians. In this Viewpoint, Younes Boudjemline and Philipp Bonhoeffer discuss the achievements so far and the future this new technique has in interventional cardiology.
A shortage of donors limits the use of heart transplantation. Despite various efforts to widen selection criteria and increase availability, the collective epidemiologic impact on donor-organ shortage has been relatively small. Approaches to date and possible ways forward, including a balance between organs and mechanical assistance, are discussed.
