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In this Journal Club, Kanaan and Copeland discuss a study showing that a high 1,25(OH)2D:25(OH)D molar ratio, indicative of vitamin D metabolism, is inversely related to the risk of highly aggressive prostate cancer in African American men.
In this Journal Club, Abbas and Kurian discuss a study showing that using iron selenide quantum dots as biometric probes is superior to conventional organic fluorophores — with higher biocompatibility and quantum yield — in detecting tumour cell growth both in vitro and in vivo.
In this Journal Club, H. Mir and S. Singh discuss a study that established the significance of signalling via the G-protein-coupled receptors CXCR1 and CXCR2 in the extrusion of neutrophil extracellular traps, which can be targeted for cancer therapy.
In this Journal Club, S. K. Singh and R. Singh discuss a study that used bioreactive, tumour microenvironment-modulating nanoparticles with doxorubicin to treat breast tumour xenograft-bearing mice, leading to reversal of immunosuppression and tumour shrinkage.
Xie and Gu discuss a study that reported the development of a CAR T therapy-based multi-antigen targeting strategy for the treatment of glioblastoma (GBM) in mice, overcoming antigen specificity and heterogeneity.
