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Cancer incidence varies in different racial and ethnic groups, and this can be partly attributed to differences in biological factors. However, identifying these factors and exploiting them to help eliminate cancer disparities has proved challenging. This Viewpoint highlights the crucial advances and challenges, as well as what the future holds, for this area of research.
Four leading tumour immunologists provide their opinions on the determinants of immunogenicity and how we might therapeutically improve tumour immunogenicity in the future.