npj Systems Biology and Applications

Identifying the essential nutritional requirements of the probiotic bacteria Bifidobacterium animalis and Bifidobacterium longum through genome-scale modeling

Marie Schöpping
Paula Gaspar
Ahmad A. Zeidan

Article 09 December 2021

Featured

Integrative computational approach identifies drug targets in CD4⁺ T-cell-mediated immune disorders

Bhanwar Lal Puniya
Rada Amin
Tomáš Helikar
Article Open Access 22 Jan 2021
Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection

Marisol Salgado-Albarrán
Erick I. Navarro-Delgado
Ernesto Soto-Reyes
Article Open Access 24 May 2021
Gene co-expression in the interactome: moving from correlation toward causation via an integrated approach to disease module discovery

Paola Paci
Giulia Fiscon
Joseph Loscalzo
Article Open Access 21 Jan 2021

Announcements

Editor Picks of 2021

Throughout the beginning of the year, the top of the homepage will be highlighting some of the key content published with the journal in 2021, as chosen by the Editor-in-Chief.
npj Systems Biology and Applications by numbers

Want to know how long your manuscript is likely to spend in peer review? Or how often our papers are cited on average? Read more about our journal metrics at this link!
Call for Papers: AI & ML

To coincide with the Nobel Turing Challenge we are currently looking for submissions focusing on artificial intelligence (AI) including machine learning (ML), as applied to system biology and biomedicine.

Browse articles

NETISCE: a network-based tool for cell fate reprogramming

Lauren Marazzi
Milan Shah
Paola Vera-Licona
Article Open Access 20 Jun 2022
Single-cell characterization of step-wise acquisition of carboplatin resistance in ovarian cancer

Alexander T. Wenzel
Devora Champa
Olivier Harismendy
Article Open Access 17 Jun 2022
Translocating proteins compartment-specifically alter the fate of epithelial-mesenchymal transition in a compartmentalized Boolean network model

Péter Mendik
Márk Kerestély
Daniel V. Veres
Article Open Access 09 Jun 2022
iUMRG: multi-layered network-guided propagation modeling for the inference of susceptibility genes and potential drugs against uveal melanoma

Yueping Ren
Congcong Yan
Jie Sun
Article Open Access 24 May 2022
Transcriptome analysis of clock disrupted cancer cells reveals differential alternative splicing of cancer hallmarks genes

Deeksha Malhan
Alireza Basti
Angela Relógio
Article Open Access 12 May 2022
A multiscale model of the regulation of aquaporin 2 recycling

Christoph Leberecht
Michael Schroeder
Dirk Labudde
Article Open Access 09 May 2022
Mapping the epithelial–immune cell interactome upon infection in the gut and the upper airways

Martina Poletti
Agatha Treveil
Tamas Korcsmaros
Article Open Access 02 May 2022
An integrated network representation of multiple cancer-specific data for graph-based machine learning

Limeng Pu
Manali Singha
Michal Brylinski
Article Open Access 29 Apr 2022
Network- and enrichment-based inference of phenotypes and targets from large-scale disease maps

Matti Hoch
Suchi Smita
Shailendra Gupta
Article Open Access 26 Apr 2022

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