Thin slices through nuclei provide an unbiased view of the complex 3D organization of mammalian genomes.
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References
Beagrie, R.A. et al. Complex multi-enhancer contacts captured by genome architecture mapping. Nature http://dx.doi.org/10.1038/nature21411 (2017).
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Rusk, N. SLICE-ing a genome's architecture. Nat Methods 14, 336–337 (2017). https://doi.org/10.1038/nmeth.4252
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DOI: https://doi.org/10.1038/nmeth.4252