Technology Features in 2020

CRISPR, now a Nobel-Prize-winning technology, comes in many flavors. And so do gRNAs.

Algorithms trained to interpret microscope data can greatly extend the information that can be derived from the resulting images, or even optimize how imaging experiments are conducted.

To better study human neurodevelopment, researchers advance organoids as brain models.

With advanced approaches to sample preparation and data analysis, scientists doing cryo-EM are starting to infer molecular movements from samples that are, literally, frozen.

There’s a growing affinity for recombinant antibodies. Some say it’s also high time for animal-free recombinants.

‘Omics pipeline builders and users face options and tough decisions.

Phase separation creates complex condensates in eukaryotic cells. To study these mysterious droplets, many disciplines come together.

To thwart SARS-CoV-2, labs hurry to hone assays, swap findings and share resources.

T cells race to the scene in cancer and infection. To tease out what is special in cancer, scientists widen their scope and tool sets.

Some -omics tools can be more accurate, sensitive or efficient than others. Yet benchmarking is no tell-all.

Microbiologists stake their claim: assessing climate change involves new ways of studying the ocean’s microbes.