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The AlphaFill algorithm transplants missing small molecules and ions from experimentally determined structures to predicted protein models in the AlphaFold protein structure database. All AlphaFill entries are available for visual inspection and download through the AlphaFill website.
This Resource presents and analyzes four datasets containing both gene expression and morphological profile data for cells subjected to hundreds to thousands of chemical or genetic perturbations and highlights their complementary nature.
This Resource presents a serial block-face EM dataset of the whole larval zebrafish brain, including automated segmentation of neurons, detection of synapses and reconstruction of circuitry for visual motion processing.
This work presents a quantitative draft of the mouse proteome and phosphoproteome constructed from 41 healthy tissues covering 15 major anatomical systems and 66 cell lines.