News & Comment

A non-invasive technique images stem cell grafts in the brain.

A new gene modifies the risk of Alzheimer's disease in people carrying the high-risk apolipoprotein E allele.

High-throughput sequencing replaces DNA microarrays in a new variation on genome-wide mapping of transcription factor binding sites.

A free online resource identifies tissue-specific expression of Drosophila genes.

Endogenous marijuana-like compounds are important in axon pathfinding in the developing brain.

High-throughput proteomics identifies a lectin important in the degeneration of neuronal processes.

Ultraviolet light alters the conformation of a glutamate analog, allowing it to bind attached receptors in a new neuron photoactivation system.

Two-dimensional images describe the spatial and temporal expression of more than 1600 C. elegans genes.

Using a proteomics approach, researchers identify 234 proteins that bind to the protein associated with Huntington's disease and may modify disease progression.

Researchers shuttle gene therapy products into the brain using ligands to receptors in the blood-brain barrier.

Epigenetic modifications recover lost memories in a mouse model of neurodegeneration.

A proteomics technique quantifies early signaling events with one-second resolution.

Receptors involved in attention strengthen working memory by closing ion channels in dendritic spines.

Regional gene expression is conserved in mouse and human brain.

Excess neurogenesis at the cost of gliogenesis may cause cognitive dysfunction in Noonan syndrome.

Two research groups use light-activated cation channels to functionally map neural circuits.

Neurons that contain the most CREB have a competitive advantage over neighboring neurons in memory formation.

Researchers generate genomic tools to help identify genes in the songbird brain.

Mutations that reduce cAMP-dependent protein kinase activity suppress memory loss in middle-aged Drosophila.

A microscopy technique from 1903 visualizes individual neurons in the context of the whole brain.