Liver spatiotemporal transcriptomics
Two studies characterize spatiotemporal transcriptional dynamics during liver homeostasis, cholestatic injury and regeneration in mice.
Two studies characterize spatiotemporal transcriptional dynamics during liver homeostasis, cholestatic injury and regeneration in mice.
Trinucleotide repeat expansions, notably CAG repeats translated into toxic polyglutamine-containing proteins, are the leading cause of spinocerebellar ataxia (SCA). New work points to a GGC repeat expansion that encodes a polyglycine-containing protein as a cause of SCA4, highlighting polyglycine disorders as an emerging human genetic disease class.