Bacterial pili are surface fibers that must resist high shearing forces to remain associated with their target. The Escherichia coli type 1 pilus chaperone FimC serves as a 'sensor', ensuring that only stable pilins become incorporated into the growing fiber.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Hannan, T.J. et al. FEMS Microbiol. Rev. 36, 616–648 (2012).
Bucior, I., Pielage, J.F. & Engel, J.N. PLoS Pathog. 8, e1002616 (2012).
Crespo, M.D. et al. Nat. Chem. Biol. 8, 707–713 (2012).
Allen, W.J., Phan, G. & Waksman, G. Curr. Opin. Struct. Biol. doi:10.1016/j.sbi.2012.02.001 (6 March 2012).
Sauer, F.G., Pinkner, J.S., Waksman, G. & Hultgren, S.J. Cell 111, 543–551 (2002).
Choudhury, D. et al. Science 285, 1061–1066 (1999).
Remaut, H. et al. Cell 133, 640–652 (2008).
Nishiyama, M. et al. EMBO J. 24, 2075–2086 (2005).
Phan, G. et al. Nature 474, 49–53 (2011).
Heras, B. et al. Nat. Rev. Microbiol. 7, 215–225 (2009).
Le Trong, I. et al. Cell 141, 645–655 (2010).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Neves, D., Dessen, A. Sensing stability. Nat Chem Biol 8, 681–682 (2012). https://doi.org/10.1038/nchembio.1026
Published:
Issue Date:
DOI: https://doi.org/10.1038/nchembio.1026