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Volume 3 Issue 5, May 2021

Neural architecture search for computational genomics

Applying deep learning models requires the tuning of network architectures for optimum performance, which can require substantial machine learning expertise. In this issue, Zijun Zhang et al. present a fully automated framework, AMBER, to design and apply convolutional neural networks for genomic sequences using neural architecture search. In an accompanying News & Views, Yi Zhang, Yang Liu and X. Shirley Liu discuss the AMBER technique and its potential to improve deep learning models in genomics.

See Zhang et al. and Zhang, Liu and Liu

Image: Simons Foundation. Cover design: Lauren Heslop.

Editorial

  • A white paper from Partnership on AI provides timely advice on tackling the urgent challenge of navigating risks of AI research and responsible publication.

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Correspondence

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Comment & Opinion

  • We spoke with Mariarosaria Taddeo, an associate professor and senior research fellow at the Oxford Internet Institute and Dstl Ethics Fellow at the Alan Turing Institute working on digital and AI ethics about two recent reports from the UK and the US on using AI in national defence and security.

    • Liesbeth Venema
    Q&A
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News & Views

  • Deep learning applied to genomics can learn patterns in biological sequences, but designing such models requires expertise and effort. Recent work demonstrates the efficiency of a neural network architecture search algorithm in optimizing genomic models.

    • Yi Zhang
    • Yang Liu
    • X. Shirley Liu
    News & Views
  • A challenge for multiscale simulations is how to link the macroscopic and microscopic length scales effectively. A new machine-learning-based sampling approach enables full exploration of macro configurations while retaining the precision of a microscale model.

    • Shangying Wang
    • Simone Bianco
    News & Views
  • State of the art neural network approaches enable massive multilingual translation. How close are we to universal translation between any spoken, written or signed language?

    • Marta R. Costa-jussà
    News & Views
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Reviews

  • Modern machine learning approaches, such as deep neural networks, generalize well despite interpolating noisy data, in contrast with textbook wisdom. Mitra describes the phenomenon of statistically consistent interpolation (SCI) to clarify why data interpolation succeeds, and discusses how SCI elucidates the differing approaches to modelling natural phenomena represented in modern machine learning, traditional physical theory and biological brains.

    • Partha P. Mitra
    Perspective
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Research

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Amendments & Corrections

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