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The D4 format for genomics datasets employs an adaptive encoding strategy based on the relatively low variance of sequence coverage. This encoding improves the speed at which these datasets can be queried for biological inquiry, while also achieving better or comparable file sizes than existing formats.
The R package barcodetrackR facilitates the analysis and visualization of clonal tracking data, and it includes a graphical user interface to allow researchers without programming experience to utilize various quantitative tools.
DNA profiles of suspects that are searched in criminal databases, such as CODIS, are often retained and can result in racial profiling. This work builds a privacy-preserving CODIS query system to support DNA profile searches while preserving individual privacy.
Scellnetor is a single-cell network enrichment method that can unravel connected molecular interaction networks to explain the progression and differentiation of developmental trajectories on a systems biology level.
