Volume 19 Issue 4, April 2014

Cover Legend: Cerebral 5-HT₄ receptor binding before and after intervention with fluxotine: Cerebral 5-HT₄ receptor binding as measured with ¹¹C-SB207145 PET in a healthy volunteer before (left) and after (right) 3 weeks of intervention with fluxotine. Intervention is associated with a decline in 5-HT₄ receptor binding. 3-D surface rendering is done on the basis of the corresponding MR brain image and the brain image is sliced to illustrate the higher 5-HT_4R binding in striatum. For more info on this topic, please refer to the article by Haahr et al. on pages 427–432.