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Pericentriolar material 1 (PCM1; red) and V5-tagged Phe607 Disrupted in Schizophrenia-1 (DISC-1: green) immunoreactivity in an untransfected (left panel) and transfected (right panel) SH-SY5Y cell. Note that the area of PCM-1 immunoreactivity at the centrosome of the untransfected cell (bright red blob, left panel) appears larger than the area of in Phe607 DISC-1 and PCM1 co-localization (smaller yellow blob, right panel). For more information on this topic, please refer to the article by Eastwood et al. on pages 556–557.