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Intestinal epithelial cells showing F-actin rich cytoplasmic extensions in cells migrating to heal a wound. Phosphorylation and activation of focal adhesion kinase (FAK) in concert with integrins and associated proteins regulates cell movement and wound repair. The image shows F-actin(red), pFAK Y861 (green) and nuclei (blue) in migrating epithelial cells.
Photo courtesy of Dr. Asma Nusrat, Department of Pathology, School of Medicine, University of Michigan. For more information, please see the article in this issue, pages 909-918.