Molecular Targets For Therapy (MTT) in 2004

Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation

• R R Rosato
• Y Dai
• S Grant

The synthetic peptide PFWT disrupts AF4–AF9 protein complexes and induces apoptosis in t(4;11) leukemia cells

• R S Srinivasan
• J B Nesbit
• C S Hemenway

Efficacy of dual-specific Bcr-Abl and Src-family kinase inhibitors in cells sensitive and resistant to imatinib mesylate

• A J Tipping
• S Baluch
• J V Melo

Proteasome inhibitor, bortezomib, potently inhibits the growth of adult T-cell leukemia cells both in vivo and in vitro

• Y Satou
• K Nosaka
• M Matsuoka

The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells

• D M Lucas
• M E Davis
• M R Grever

Topoisomerase IIα expression in mantle cell lymphoma: a marker of cell proliferation and a prognostic factor for clinical outcome

• C Schrader
• P Meusers
• M Tiemann

The conjugate Rituximab/saporin-S6 completely inhibits clonogenic growth of CD20-expressing cells and produces a synergistic toxic effect with Fludarabine

• L Polito
• A Bolognesi
• F Stirpe

Hox expression in AML identifies a distinct subset of patients with intermediate cytogenetics

• J Roche
• C Zeng
• H A Drabkin

Identification of a gene element essential for leukemia-specific expression of transgenes

• N Hosen
• M Yanagihara
• H Sugiyama