Browse Articles

  • Article | | open

    The hydration and ion pairing of metal-organic supramolecular cages plays a crucial role in their interaction with guests but is difficult to quantify with standard analysis. Here, the authors show that microwave microfluidics to measure the hydration and ion pairing of two tetrahedral metal-organic cages.

    • Angela C. Stelson
    • , Cynthia M. Hong
    • , Mitchell C. Groenenboom
    • , Charles A. E. Little
    • , James C. Booth
    • , Nathan D. Orloff
    • , Robert G. Bergman
    • , Kenneth N. Raymond
    • , Kathleen A. Schwarz
    • , F. Dean Toste
    •  & Christian J. Long
  • Article | | open

    The exfoliation of covalent organic frameworks is a potential route to interesting two-dimensional materials. Here, the authors report a strategy incorporating metal ions and axial ligands to facilitate exfoliation of porphyrin COFs, and examine the photocatalytic activity of the resulting nanomaterials.

    • Zeyu Fan
    • , Kota Nomura
    • , Mingshan Zhu
    • , Xinxi Li
    • , Jiawei Xue
    • , Tetsuro Majima
    •  & Yasuko Osakada
  • Article | | open

    Reactions of ozone with human skin oils impact indoor air quality by depleting ozone and forming semi-volatile organic compounds. Here, the authors examine the impact of clothing on indoor air composition and human exposure by integrating indoor chemistry modeling over a range of spatial and temporal scales.

    • Pascale S. J. Lakey
    • , Glenn C. Morrison
    • , Youngbo Won
    • , Krista M. Parry
    • , Michael von Domaros
    • , Douglas J. Tobias
    • , Donghyun Rim
    •  & Manabu Shiraiwa
  • Article | | open

    Catalytic oxygen reduction is an important process for clean energy production. Here the catalytic activity of trioxotriangulenes for the oxygen reduction reaction is shown to be correlated with their redox potential, offering a potential route to rationally tune their catalytic activity.

    • Tsuyoshi Murata
    • , Kenji Kotsuki
    • , Hirotaka Murayama
    • , Ryotaro Tsuji
    •  & Yasushi Morita
  • Article | | open

    Self-assembled glycopeptides are increasingly used as biomaterials. Here the self-assembly of glycosylated peptides under crowded conditions is shown to yield laterally aligned fibres which exhibit superior resistance towards non-specific binding of proteins and cells.

    • Antonietta Restuccia
    • , Dillon T. Seroski
    • , Karen L. Kelley
    • , Christopher S. O’Bryan
    • , Justin J. Kurian
    • , Kevin R. Knox
    • , Shaheen A. Farhadi
    • , Thomas E. Angelini
    •  & Gregory A. Hudalla
  • Article | | open

    Aqueous solutions of ionic liquids can undergo thermally-controlled phase separation, but the microscopic processes driving this are not fully understood. Here a combination of experimental methods and molecular dynamics simulations are used to probe the influence of local structure on the formation of micron-scale clustering.

    • Hyungmook Kang
    • , David E. Suich
    • , James F. Davies
    • , Aaron D. Wilson
    • , Jeffrey J. Urban
    •  & Robert Kostecki
  • Article | | open

    Zinc oxide exhibits a sub-band-gap green emission, the origin of which is widely debated. Here a combination of photophysical and conductivity analyses reveal that adsorbed superoxide may be responsible for the strong green emission of zinc oxide.

    • Jason A. Röhr
    • , Jacinto Sá
    •  & Steven J. Konezny
  • Article | | open

    Cerium–zirconium solids are key materials in heterogeneous catalysis but understanding oxygen storage and diffusion in bulk samples is a challenge. Here the authors use three-dimensional hard X-ray spectro-ptychography and unsupervised learning to achieve nanoscale chemical imaging of reaction events.

    • Makoto Hirose
    • , Nozomu Ishiguro
    • , Kei Shimomura
    • , Duong-Nguyen Nguyen
    • , Hirosuke Matsui
    • , Hieu Chi Dam
    • , Mizuki Tada
    •  & Yukio Takahashi
  • Article | | open

    The triple phase boundary structure in solid-oxide fuel cells largely determines the thermodynamics and kinetics of electrochemical processes therein. Here the authors use atomic-resolution microscopy and reaction dynamics simulation to reveal three discrete hydrogen oxidation reaction pathways.

    • Shu-Sheng Liu
    • , Leton C. Saha
    • , Albert Iskandarov
    • , Takayoshi Ishimoto
    • , Tomokazu Yamamoto
    • , Yoshitaka Umeno
    • , Syo Matsumura
    •  & Michihisa Koyama
  • Article | | open

    The reduction of CO2 by electro- and biocatalysis offers a promising route to the sustainable production of chemicals and fuels. Here, the integration of methanogenic or homoacetogenic microbes with earth-abundant electrodes allows robust, rapid, and selective CO2 reduction with coulombic efficiencies of up to 100%.

    • Frauke Kracke
    • , Andrew Barnabas Wong
    • , Karen Maegaard
    • , Joerg S. Deutzmann
    • , McKenzie A. Hubert
    • , Christopher Hahn
    • , Thomas F. Jaramillo
    •  & Alfred M. Spormann
  • Article | | open

    Mass transfer of guest molecules in nanoporous crystalline materials is dominated by surface barriers and intracrystalline diffusion. Here the authors derive an approximate expression of uptake rate relying solely on surface permeability, offering an approach to directly quantify both effects.

    • Mingbin Gao
    • , Hua Li
    • , Miao Yang
    • , Shushu Gao
    • , Pengfei Wu
    • , Peng Tian
    • , Shutao Xu
    • , Mao Ye
    •  & Zhongmin Liu
  • Article | | open

    Catalytic insertion of carbon dioxide into epoxides offers a useful route to cyclic carbonates. Here cobalt(III) ONO pincer complexes are shown to catalyze this reaction at ambient pressure with turnover numbers of up to 200,000.

    • Habib Ullah
    • , Bibimaryam Mousavi
    • , Hussein A. Younus
    • , Zafar A. K. Khattak
    • , Somboon Chaemchuen
    • , Suleman Suleman
    •  & Francis Verpoort
  • Article | | open

    Activation of C-H bonds through visible light irradiation remains a challenge in attaining energy efficient organic transformations. Here the authors show an osmium(VI) nitrido complex which can perform nitrogenation of cyclic alkanes and arenes by acting as a strong electrophile in the excited state.

    • Jing Xiang
    • , Xin-Xin Jin
    • , Qian-Qian Su
    • , Shun-Cheung Cheng
    • , Chi-Chiu Ko
    • , Wai-Lun Man
    • , Minying Xue
    • , Liangliang Wu
    • , Chi-Ming Che
    •  & Tai-Chu Lau
  • Article | | open

    The relationship between molecular motion and catalysis in enzymes is debated. Here, simulations of cyclophilin A and three catalytically-impaired mutants reveal a nanosecond-scale interconversion between active and inactive conformations, orders of magnitude faster than previously suggested.

    • Pattama Wapeesittipan
    • , Antonia S. J. S. Mey
    • , Malcolm D. Walkinshaw
    •  & Julien Michel
  • Article | | open

    Metal-organic frameworks are commonly proposed as potential sensors for explosive compounds but the precise sensing mechanism remains unclear. Here, the authors experimentally assess the fluorescence-quenching mechanisms of a hydroxyl-functionalized MOF, as it interacts with nitroaromatics.

    • Amitosh Sharma
    • , Dongwook Kim
    • , Jae-Heon Park
    • , Surajit Rakshit
    • , Junmo Seong
    • , Gyoung Hwa Jeong
    • , Oh-Hoon Kwon
    •  & Myoung Soo Lah
  • Article | | open

    The deactivation of zeolite catalyst by sulfur contaminants is a major problem in direct olefin upgrading of crude oil. Here the authors perform mechanistic analyses of zeolite ZSM-5 catalysts to reveal the detrimental effect of sulfur on silver and gallium Lewis acid sites in the catalyst.

    • Jonathan H. Harrhy
    • , Aiguo Wang
    • , Jack S. Jarvis
    • , Peng He
    • , Shijun Meng
    • , Matthew Yung
    • , Lijia Liu
    •  & Hua Song
  • Article | | open

    Polyphenols are widely studied as potential drugs for Alzheimer’s disease, but their development is limited by poor bioavailability. Here polyphenolic analogues of the Alzheimer's disease drug rivastigmine are shown to inhibit both cholinesterase and amyloid beta fibrillation in vitro and in vivo in a C. elegans model, providing a potentially general route for the development of polyphenol-based drugs.

    • Satish N. Dighe
    • , Eugenio De la Mora
    • , Stephen Chan
    • , Srinivas Kantham
    • , Gawain McColl
    • , Jared A. Miles
    • , Suresh Kumar Veliyath
    • , B. Yogi Sreenivas
    • , Zeyad D. Nassar
    • , Israel Silman
    • , Joel L. Sussman
    • , Martin Weik
    • , Ross P. McGeary
    • , Marie-Odile Parat
    • , Xavier Brazzolotto
    •  & Benjamin P. Ross
  • Article | | open

    The low toxicity of indium phosphide quantum dots makes them attractive candidates for biomedical applications but they typically exhibit low low photoluminescent quantum yield in aqueous media. Here the authors report a controlled-cooling based synthetic method which produces super bright quantum dots.

    • Mitchell T. Clarke
    • , Francesco Narda Viscomi
    • , Thomas W. Chamberlain
    • , Nicole Hondow
    • , Ali M. Adawi
    • , Justin Sturge
    • , Steven C. Erwin
    • , Jean-Sebastien G. Bouillard
    • , Sudarsan Tamang
    •  & Graeme J. Stasiuk
  • Article | | open

    The synthesis of tri- and tetra-aryl alkenes is limited by poor regio- and stereoselectivity. Here MIDA boronate-substituted aryl alkynes are used to achieve regioselective three-component diarylation of the alkyne and to provide a cross-coupling handle for subsequent elaboration to tri- or tetra-substituted products.

    • E. Emily Lin
    • , Jia-Qiang Wu
    • , Felix Schäfers
    • , Xiao-Xuan Su
    • , Ke-Feng Wang
    • , Ji-Lin Li
    • , Yunyun Chen
    • , Xin Zhao
    • , Huihui Ti
    • , Qingjiang Li
    • , Tian-Miao Ou
    • , Frank Glorius
    •  & Honggen Wang
  • Article | | open

    There is a continuous demand to develop new procedures for the synthesis of pristine graphene for device applications. Here the authors report gold catalyzed in situ formation of graphene from hydrocarbon contaminants in a transmission electron microscope within a few milliseconds at room temperature.

    • Ignacio G. Gonzalez-Martinez
    • , Alicja Bachmatiuk
    • , Thomas Gemming
    • , Barbara Trzebicka
    • , Zhongfan Liu
    •  & Mark H. Rummeli
  • Q&A | | open

    The importance of collaboration and good working relationships is unquestionable in chemistry, and is vital for the effective publication of research articles. In this series of Q&A’s we talk to people involved in all aspects of the process and explore the relationships between them. Here we discuss the mentor-mentee relationship with Professor Gisbert Schneider and Dr Francesca Grisoni (both ETH Zurich).

  • Editorial | | open

    This month Communications Chemistry celebrates its first anniversary of publishing research, reviews and commentary in all areas of the chemical sciences. Here we look back at the past 12 months of the journal and think about the many things still to achieve.

  • Q&A | | open

    The importance of collaboration and good working relationships is unquestionable in our field, and is vital for the effective publication of research articles. In this series of Q&A’s we talk to people involved in all aspects of the process and explore the relationships between them. Here we discuss interactions between authors and reviewers with Professor Jennifer Andexer (University of Freiburg) and Professor Wolfgang Kroutil (University of Graz).

  • Article | | open

    The direct glycosylation of ribose by nucleobases offers an intuitive route to nucleosides, but is known to be challenging under prebiotically plausible reaction conditions. Here, the addition of amino acids is shown to influence the product distribution, and a dynamic exchange of nucleobases between nucleosides and nucleotides is observed.

    • Irene Suárez-Marina
    • , Yousef M. Abul-Haija
    • , Rebecca Turk-MacLeod
    • , Piotr S. Gromski
    • , Geoffrey J. T. Cooper
    • , Andrea Olivé Olivé
    • , Stephanie Colón-Santos
    •  & Leroy Cronin
  • Article | | open

    It is important to identify heterogeneous catalyst compositions which minimize use of precious metals. Here the authors analyse the size-activity behaviour of platinum-based formaldehyde oxidation catalysts, identifying a volcano relationship with nanometer scale nanoclusters being the most effective.

    • Xiucheng Sun
    • , Jian Lin
    • , Yang Chen
    • , Yuehan Wang
    • , Lin Li
    • , Shu Miao
    • , Xiaoli Pan
    •  & Xiaodong Wang
  • Article | | open

    Mechanically interlocked molecules are widely studied, but the pathways by which they assemble are less well understood. Here the formation process of a quadruply-locked Pd4L8 cage is studied by NMR and mass spectrometry, with intermediates inferred by kinetic analysis.

    • Tomoki Tateishi
    • , Yuichi Yasutake
    • , Tatsuo Kojima
    • , Satoshi Takahashi
    •  & Shuichi Hiraoka
  • Article | | open

    Fluorinated solvents such as hexafluoroisopropanol (HFIP) are often useful in reactions involving radical cations. Here the role of HFIP in photoredox and electrochemical Diels-Alder reactions is explored experimentally and theoretically, and attributed to solvation of anions to reduce their nucleophilicity.

    • Naoki Shida
    • , Yasushi Imada
    • , Shingo Nagahara
    • , Yohei Okada
    •  & Kazuhiro Chiba
  • Article | | open

    The Strecker reaction is thought to offer a prebiotically plausible synthesis of amino acids, but is reversible at the high or low pH ranges needed to promote reactivity. Here the reaction of hydrogen cyanide and diamidophosphate is shown to provide stable phosphorylated amino acid precursors at neutral pH, which can be hydrolysed to amino acids or thiolysed to thioamides.

    • Kathryn Ashe
    • , Christian Fernández-García
    • , Merina K. Corpinot
    • , Adam J. Coggins
    • , Dejan-Krešimir Bučar
    •  & Matthew W. Powner
  • Article | | open

    Probing intermolecular interactions and film heterogeneity in organic semiconductors is challenging. Here, the authors use micro-Raman spectroscopy to assign vibrational modes of isomerically pure functionalized anthradithiophenes, which are then used to image crystalline sub-domains in mixed-isomer samples.

    • Chiung-Wei Huang
    • , Xiao You
    • , Peter J. Diemer
    • , Anthony J. Petty II
    • , John E. Anthony
    • , Oana D. Jurchescu
    •  & Joanna M. Atkin
  • Article | | open

    Isoprene is a key compound emitted into the atmosphere, which reacts rapidly with hydroxyl radicals and contributes to aerosol formation. Here the authors conduct flow tube measurements to observe the early stages of isoprene oxidation product formation in low hydroperoxy radical and nitric oxide environments.

    • Torsten Berndt
    • , Noora Hyttinen
    • , Hartmut Herrmann
    •  & Armin Hansel
  • Article | | open

    Structural phase transitions induced by external stimuli play crucial roles in controlling the functions of solid-state materials. Here the authors report the photo-triggered phase transition of a photochromic chiral salicylideneamine crystal, and probe the local effects driving the transition.

    • Takuya Taniguchi
    • , Hiroyasu Sato
    • , Yuki Hagiwara
    • , Toru Asahi
    •  & Hideko Koshima
  • Article | | open

    The ceramide transport protein CERT is of potential therapeutic interest but is typically targeted using ceramide-derived ligands. Here the authors use virtual screening and a quantitative surface plasmon resonance assay to identify ceramide-nonmimetic inhibitors of a CERT subdomain and test their activity in live cells.

    • Naoki Nakao
    • , Masaharu Ueno
    • , Shota Sakai
    • , Daichi Egawa
    • , Hiroyuki Hanzawa
    • , Shohei Kawasaki
    • , Keigo Kumagai
    • , Makoto Suzuki
    • , Shu Kobayashi
    •  & Kentaro Hanada
  • Article | | open

    Stable single-atomic and noble-metal free catalysts are crucial in light driven hydrogen evolution but their behavior upon visible light irradiation remains unclear. Here the authors develop and analyze atomic palladium on graphitic carbon nitride with enhanced catalytic activity under visible light.

    • Liping Liu
    • , Xi Wu
    • , Li Wang
    • , Xuejun Xu
    • , Lin Gan
    • , Zhichun Si
    • , Jia Li
    • , Qun Zhang
    • , Yuxiang Liu
    • , Yanyan Zhao
    • , Rui Ran
    • , Xiaodong Wu
    • , Duan Weng
    •  & Feiyu Kang
  • Article | | open

    The oxidative cleavage of the C–C bonds in 1,2-diols is an important transformation but lacks a recyclable, mild aerobic catalytic system. Here the authors present atomically dispersed cobalt on N-doped carbon to deliver improved catalytic activity and recyclability, and probe the reaction pathway.

    • Huihui Luo
    • , Lianyue Wang
    • , Sensen Shang
    • , Jingyang Niu
    •  & Shuang Gao
  • Article | | open

    Several catalytic methods for N-formylation of amines using noble metals or manganese pincer complexes are known. Here an air-stable and reusable chromium-based polyoxometalate is shown to catalyze the N-formylation of amines and diamines using methanol and hydrogen peroxide.

    • Han Yu
    • , Zhikang Wu
    • , Zheyu Wei
    • , Yongyan Zhai
    • , Shi Ru
    • , Qixin Zhao
    • , Jingjing Wang
    • , Sheng Han
    •  & Yongge Wei
  • Article | | open

    Phase change random access memory relies on phase transformation, from a metastable rock salt structure to a stable hexagonal structure, details of which remain unclear. Here the authors use atomic resolution energy dispersive X-ray spectroscopy to probe the atomic-level rearrangements during the phase transition.

    • Yonghui Zheng
    • , Yong Wang
    • , Tianjiao Xin
    • , Yan Cheng
    • , Rong Huang
    • , Pan Liu
    • , Min Luo
    • , Zaoli Zhang
    • , Shilong Lv
    • , Zhitang Song
    •  & Songlin Feng
  • Article | | open

    Copper(II)-superoxide complexes are known to behave as electrophiles but there are few examples of nucleophilic reactivity by such species. Here a mononuclear copper(II)-superoxide species is shown to promote simple aldol reactions, and this reactivity is found to be sensitive to minor changes to the ligand structure.

    • Tsukasa Abe
    • , Yuta Hori
    • , Yoshihito Shiota
    • , Takehiro Ohta
    • , Yuma Morimoto
    • , Hideki Sugimoto
    • , Takashi Ogura
    • , Kazunari Yoshizawa
    •  & Shinobu Itoh
  • Article | | open

    Oxygen vacancies in metal oxide based catalytic materials are pivotal to improving their performance. Here the authors use density functional theory and experimental data to show that introduction of hydroxyl groups in clay-supported cobalt oxides can introduce oxygen vacancies and enhance its catalytic activity.

    • Qihang Zhao
    • , Liangjie Fu
    • , Denghui Jiang
    • , Jing Ouyang
    • , Yuehua Hu
    • , Huaming Yang
    •  & Yunfei Xi
  • Article | | open

    Liquid domains can coexist within lipid membranes, and directly manipulating them in situ may offer a useful tool. Here optical tweezers are used to directly move liquid-ordered domains within the lipid bilayers of individual giant vesicles.

    • Mark S. Friddin
    • , Guido Bolognesi
    • , Ali Salehi-Reyhani
    • , Oscar Ces
    •  & Yuval Elani
  • Article | | open

    The coupling between excited state intramolecular proton transfer and excimer formation is a phenomenon of fundamental importance but rarely observed. Here the authors observe this interaction in thiazole based organic crystals using a combination of steady-state and time-resolved spectroscopic techniques.

    • Yu-Chen Wei
    • , Zhiyun Zhang
    • , Yi-An Chen
    • , Cheng-Ham Wu
    • , Zong-Ying Liu
    • , Ssu-Yu Ho
    • , Jiun-Chi Liu
    • , Jia-An Lin
    •  & Pi-Tai Chou
  • Article | | open

    Rotenoid natural products have attracted interest as synthetic targets. Here N-heterocyclic carbene-catalysed dynamic kinetic resolution is used to rapidly and enantioselectively assemble the rotenoid core, enabling the modular asymmetric total synthesis of several rotenoid natural products

    • Saima Perveen
    • , Shuang Yang
    • , Miao Meng
    • , Weici Xu
    • , Guoxiang Zhang
    •  & Xinqiang Fang
  • Article | | open

    Polyoxometalate based solids are promising candidates for proton-conducting electrolytes but their low durability and low proton conductivities remains an on-going challenge. Here the authors describe the preparation of polyoxometalate-based solids with much improved stability and proton conductivities.

    • Tsukasa Iwano
    • , Satoru Miyazawa
    • , Ryota Osuga
    • , Junko N. Kondo
    • , Kayako Honjo
    • , Takashi Kitao
    • , Takashi Uemura
    •  & Sayaka Uchida