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In this Perspective, Longxin Ren and co-authors summarise the role of circular RNAs in disease and discuss recent insights into how circular RNAs are metabolised in the cell.
Zhang and Northoff revisit the findings of global signal in fMRI from healthy and clinical populations and suggest that a dual-layer model of global signal, which takes into account both background and surface layer, may be more accurate than a single-layer view
In this Perspective, Molina-Gonzalez and co-authors discuss the contribution of oligodendrocyte injury to neurological disease and the potential for their therapeutic targeting.
A reassessment of early trilobite phylogenetic relationships and palaeobiogeographic patterns suggests that a cryptic evolutionary history is unlikely for this group. The abrupt appearance of trilobites is likely to closely reflect their evolutionary origins, and may be explained by survivorship biases inherent in the fossil record.
A Perspective highlights current evidence that supports oligodendrocytes and their progenitors’ involvement in cognition and proposes that our understanding of learning and memory can be expanded beyond the classic view of synaptic plasticity to a system-wide network function.
Microglia “heterogeneity” is often described in the literature, but a clear understanding of what “heterogeneity” entails is essential to avoid confusion among researchers.
In this Perspective, the authors discuss how state-of-the-art three-dimensional mapping technologies such as fine-scale terrestrial laser scanning can help us understand the theories of plant forms.
Colzato, Beste and Hommel discuss the possibility of a theoretical framework which considers the positive potential of selective cognitive dysfunction. They suggest a two-step approach to identify the potential and develop the corresponding training.
The study of animal societies has been increasingly explored with social network analysis. In this Perspective, the importance of these networks in directing conservation efforts of fish is highlighted.
Al-Aghbar et al propose a TCR bending mechanosignal model that demonstrates how local mechanical membrane bending may influence T cell receptor binding events and thus T-cell activation.
